33 Biology jobs in Singapore

Join to apply for the Research Fellow (Structural Biology) role at Nanyang Technological University Singapore

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Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore

The School of Biological Sciences (SBS), part of the College of Science, was established in 2002 with a mission to advance biological and biomedical sciences. At SBS, our research spans various areas, including infectious diseases, immunology, neurodegenerative diseases, telomere biology, and genome function. Over the years, SBS has attracted talented individuals from around the world and Singapore to join as scientific leaders and researchers.

For more details, please view are seeking a highly motivated Research Fellow to join our dynamic team at the School of Biological Sciences, Nanyang Technological University, Singapore. This role focuses on elucidating the 3D structures of corneal amyloid using advanced structural biology techniques. The successful candidate will contribute to cutting-edge research at the intersection of structural biology and biomedical science, with a particular emphasis on NMR spectroscopy and cryo-electron microscopy (cryo-EM).

Key Responsibilities

• Conduct research on corneal amyloids, including their structural characterization using advanced techniques such as NMR and cryo-EM.
• Develop and refine methodologies to investigate amyloid formation and its role in disease pathology.
• Collaborate with interdisciplinary teams, including clinical and animal model researchers, to advance amyloid research.
• Publish research findings in peer-reviewed journals and contribute to scientific knowledge dissemination.
• Provide mentorship and guidance to post-graduate students and junior researchers.
  
  

• PhD degree in Structural Biology, Biochemistry or related field
• Hands-on experience with NMR spectroscopy and cryo-EM for structural characterization.
• Prior completion of a laboratory animal handling course is highly preferred.
• Strong written and verbal communication skills, with the ability to present research findings effectively.
• Demonstrated ability to work independently, think critically, and develop solutions under tight deadlines.
• Proven ability to collaborate in a dynamic, multidisciplinary research environment.
  
  

• Seniority level Entry level

• Employment type Full-time

• Job function Research, Analyst, and Information Technology
• Industries Higher Education

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Geylang, Central Singapore Community Development Council, Singapore 2 months ago

Boon Lay, West Region, Singapore 23 hours ago

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Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The Synthetic Biology Translational Research Programme (TRP) at the National University of Singapore Yong Loo Lin School of Medicine is seeking talented postdoctoral or research fellows to join our team.

Synthetic Biology TRP – Research Fellow

The Synthetic Biology Translational Research Programme (TRP) focuses on engineering red blood cells for therapeutic applications, including drug delivery, immune modulation, and gene therapy. We are developing novel erythrocyte-based platforms that leverage the unique properties of RBCs for synthetic biology and biomedical innovation.

We invite applications for a highly motivated Research Fellow (RF) to work closely with the Principal Investigator and a multidisciplinary team. The position is offered on an initial one-year contract, renewable subject to performance and funding. A Ph.D. in cell biology, molecular biology, synthetic biology, or a related field is required.

Key Responsibilities

1. RBC Genomics and TranscriptomicsAnalyze gene expression and genomic regulation of erythroid differentiation.
   Characterize key transcriptional and epigenetic programs governing RBC development and function.
   
   RBC Engineering and Expression SystemsDevelop workflows for genetic modification of erythroid progenitors and immortalized RBC lines.
   Optimize lentiviral and non-viral gene delivery systems to express therapeutic payloads in RBCs.
   
   Protein Loading and Display in RBCsEngineer red blood cells to load or surface-display proteins, peptides, or other biologics.
   Evaluate protein stability, localization, and bioactivity post-engineering.
   
   RBC-based Therapeutic DevelopmentDesign and execute functional assays to assess therapeutic efficacy of engineered RBCs.
   Collaborate on in vivo models to evaluate biodistribution, immune responses, and pharmacodynamics
   Mentorship & Training
   • Supervise and mentor research assistants, graduate students, and undergraduate interns
   Additional Duties
   • Undertake other tasks assigned by the Principal Investigator or project leads as needed.
   

The applicant should:

• Hold a PhD in Biotechnology, Molecular Biology, Biochemistry, RNA Biology, or a related field.

Essential Qualifications & Attributes

Red Blood Cell Engineering Experience

• Hands-on experience with primary erythroid cultures, immortalized erythroid progenitor cell lines, or ex vivo RBC production systems.
• Skilled in flow cytometry, magnetic separation, and enucleation assays for erythroid lineage tracking and quality control.
• Familiarity with ethical guidelines and biosafety considerations in handling blood-derived materials and genetically modified cells.

Synthetic Biology Skills for RBC Platforms

• Proficiency in genetic construct design, vector engineering, and transgene integration for expression in erythroid cells.
• Experience with protein or nucleic acid loading strategies in mature RBCs or erythroid precursors.
• Competence in troubleshooting gene expression systems and optimizing yield, stability, and functional output of engineered RBCs.

Experimental Design & Execution

- Ability to design and conduct RNA/protein expression analyses, enzymatic assays, and studies of RNA chemical modifications.

Research Excellence

- Strong record of high‑impact, peer‑reviewed international publications.

Professional Qualities

- Independent, highly motivated, and detail‑oriented.

- Effective collaborator in multidisciplinary research environments.

Remuneration will be commensurate to the candidate's qualifications and experience. Informal enquiries are welcome and should be made to Ms Suhana Sulaiman , at

Formal application: Please submit your application, indicating job reference number and current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of 3 referees). Only shortlisted candidates will be notified.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The Synthetic Biology Translational Research Programme (TRP) at the National University of Singapore Yong Loo Lin School of Medicine is seeking talented postdoctoral or research fellows to join our team.

Synthetic Biology TRP – Research Fellow

The Synthetic Biology Translational Research Programme (TRP) focuses on engineering red blood cells for therapeutic applications, including drug delivery, immune modulation, and gene therapy. We are developing novel erythrocyte-based platforms that leverage the unique properties of RBCs for synthetic biology and biomedical innovation.

We invite applications for a highly motivated Research Fellow (RF) to work closely with the Principal Investigator and a multidisciplinary team. The position is offered on an initial one-year contract, renewable subject to performance and funding. A Ph.D. in cell biology, molecular biology, synthetic biology, or a related field is required.

1. RBC Genomics and TranscriptomicsAnalyze gene expression and genomic regulation of erythroid differentiation.
   Characterize key transcriptional and epigenetic programs governing RBC development and function.
   
2. RBC Engineering and Expression SystemsDevelop workflows for genetic modification of erythroid progenitors and immortalized RBC lines.
   Optimize lentiviral and non-viral gene delivery systems to express therapeutic payloads in RBCs.
   
3. Protein Loading and Display in RBCsEngineer red blood cells to load or surface-display proteins, peptides, or other biologics.
   Evaluate protein stability, localization, and bioactivity post-engineering.
   
4. RBC-based Therapeutic DevelopmentDesign and execute functional assays to assess therapeutic efficacy of engineered RBCs.
   Collaborate on in vivo models to evaluate biodistribution, immune responses, and pharmacodynamics.
   
5. Mentorship & Training
   • Supervise and mentor research assistants, graduate students, and undergraduate interns.
6. Additional Duties
   • Undertake other tasks assigned by the Principal Investigator or project leads as needed.

The applicant should:

• Hold a PhD in Biotechnology, Molecular Biology, Biochemistry, RNA Biology, or a related field.

Essential Qualifications & Attributes

Red Blood Cell Engineering Experience

• Hands-on experience with primary erythroid cultures, immortalized erythroid progenitor cell lines, or ex vivo RBC production systems.
• Skilled in flow cytometry, magnetic separation, and enucleation assays for erythroid lineage tracking and quality control.
• Familiarity with ethical guidelines and biosafety considerations in handling blood-derived materials and genetically modified cells.

Synthetic Biology Skills for RBC Platforms

• Proficiency in genetic construct design, vector engineering, and transgene integration for expression in erythroid cells.
• Experience with protein or nucleic acid loading strategies in mature RBCs or erythroid precursors.
• Competence in troubleshooting gene expression systems and optimizing yield, stability, and functional output of engineered RBCs.

Experimental Design & Execution

- Ability to design and conduct RNA/protein expression analyses, enzymatic assays, and studies of RNA chemical modifications.

Research Excellence

- Strong record of high‑impact, peer‑reviewed international publications.

Professional Qualities

- Independent, highly motivated, and detail‑oriented.

- Effective collaborator in multidisciplinary research environments.

Remuneration will be commensurate to the candidate's qualifications and experience. Informal enquiries are welcome and should be made to

Ms Suhana Sulaiman , at

Formal application: Please submit your application, indicating job reference number and current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of 3 referees). Only shortlisted candidates will be notified.

Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore

The School of Biological Sciences (SBS), part of the College of Science, was established in 2002 with a mission to advance biological and biomedical sciences. At SBS, our research spans various areas, including infectious diseases, immunology, neurodegenerative diseases, telomere biology, and genome function. Over the years, SBS has attracted talented individuals from around the world and Singapore to join as scientific leaders and researchers.

For more details, please view .

A Research Assistant position is available in the laboratory of Professor Julien Lescar at SBS.

Key Responsibilities:

• Protein expression and purification in E. coli system.
• Macromolecule functional characterization and other binding analysis experiments.
• Structural studies using X-Ray crystallography and Cryo-EM (sample preparation, sample screening, data collection and data processing).
• Assist in drafting research proposals and manuscripts.
• Assist in general lab activities, including but not limited to safety and risk assessment, equipment maintenance, procurement and other related duties.

Job Requirements:

• Bachelor’s degree in Biological Sciences or related fields.
• Basic knowledge and hands-on experience with molecular cloning, protein expression, and purification techniques is highly preferred.
• Experience in X-Ray crystallography and Cryo-EM is a plus.
• Strong organizational skills, attention to detail, and the ability to work independently as well as in a team.
• Passion for scientific research and innovation.

The College of Science seeks a diverse and inclusive workforce and is committed to equality of opportunity. We welcome applications from all and recruit on the basis of merit, regardless of age, race, gender, religion, marital status and family responsibilities, or disability.

We regret that only shortlisted candidates will be notified.

Join to apply for the Senior Research Fellow (Molecular Biology/Biochemistry & Structural Biology) role at Nanyang Technological University Singapore

Join to apply for the Senior Research Fellow (Molecular Biology/Biochemistry & Structural Biology) role at Nanyang Technological University Singapore

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NTU Institute of Structure Biology (NISB) provides a complete pipeline for Structural Biology to accelerate discovery in basic and applied Bioscience.

At NISB, we aim to integrate a comprehensive set of Structural Biology tools to address fundamental questions in biology, to understand human diseases and to accelerate structure-based drug discovery. We have the expertise and equipment to bring your gene of interest from plasmid to atomic level structure using a series of state-of-the art platforms for Protein expression, biophysical characterization and imaging using cryo-EM, tomography or X-ray crystallography.

For more details, please view Responsibilities

We are looking for a Senior Research Fellow to play a leading role in running NISB in close partnership with the NISB Director. This role offers a unique opportunity to drive impactful research while fostering collaboration and innovation in a dynamic scientific environment. The job scope includes:

• Collaborate with various academic and industry users of NISB facilities to define their needs and to help design and perform the experiments together with the core NISB team;
• Lead the NISB core team to ensure timely delivery of quality samples and deliverables (overexpressed protein, structure with proper protocol and documentation;
• Work with the core team to maintain accurate and comprehensive reporting and documentation for tasks commissioned by academic and industry users;
• Support NISB Director in advocating for NISB’s activities and technological platforms to enhance visitibility and engagement with stakeholders;
• Contribute to in-house research and platform technological development : the successful candidate can pursue independent research in structural biology or biotechnology aligned with the institute’s interest in protein structure and engineering.
  
  

• A PhD degree in Molecular Biology, Biochemistry, Structural Biology, Biotechnology or related field
• At least 2 years of relevant experiences in similar role / technical hands-on experience in protein related work
• Possesses international experience, acquired through postdoctoral experience documented by relevant publications
• Good written and oral communication skills
• Proficiency in handling software to collect and process Structural Biology data (XDS, CCP4, Phenix for X-ray crystallography and Cryosparc, Relion for Cryo-EM
• Very good publication record in international peer reviewed journals in relevant fields
• Strong ability to work independently, to develop solutions under strict timelines, meticulous and eye for details Excellent organizational and time management skills
• Demonstrates strong collaboration skills by working effectively with diverse academic and industry stakeholders, as well as thriving in a fast-paced environment alongside the NISB core team
  
  

• Seniority level Mid-Senior level

• Employment type Full-time

• Job function Research, Analyst, and Information Technology
• Industries Higher Education

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Get notified about new Senior Biologist jobs in Singapore, Singapore .

Pioneer, West Region, Singapore 2 weeks ago

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• To deliver effective and engaging lessons
• To establish a positive learning environment that encourages analytical thinking and independent thinking
• To adopt different modes of assessment
• University degree with at least honours degree in the relevant subject area
• Possess teacher-training qualifications, i.e PGDE or equivalent
• Preferably former MOE teachers with experience teaching in the subject area at Secondary Science Level

Research Fellow (Synthetic Biology & Enzyme Design)

Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore

The School of Biological Sciences (SBS), part of the College of Science, was established in 2002 with a mission to advance biological and biomedical sciences. At SBS, our research spans various areas, including infectious diseases, immunology, neurodegenerative diseases, telomere biology, and genome function. Over the years, SBS has attracted talented individuals from around the world and Singapore to join as scientific leaders and researchers.

We are seeking a highly motivated Research Fellow (RF) to join our team in the field of synthetic biology and enzyme design. This role focuses on developing novel biocatalysts and synthetic pathways through cutting-edge research. The successful candidate will contribute to impactful projects while gaining exposure to advanced methodologies in synthetic biology.

Key Responsibilities:

1. Lead the design, construction, and optimization of synthetic biological systems and enzyme engineering workflows.
2. Execute advanced molecular biology techniques, including DNA manipulation, PCR, and molecular cloning.
3. Conduct protein expression, purification, and characterization using methods such as spectrophotometry, HPLC, and SDS-PAGE.
4. Analyze experimental data, maintain meticulous records, and contribute to manuscript preparation for high-impact journals.

Job Requirements:

1. PhD in Biochemistry, Molecular Biology, Synthetic Biology, or a related field (completed or near completion).
2. Strong expertise in molecular cloning, protein engineering, and synthetic biology tools (e.g., CRISPR, metabolic pathway design).
3. Ability to work independently, solve complex problems, and manage multiple priorities in a fast-paced research environment.

Interested candidates should submit the following documents:

1. A cover letter detailing research interests and relevant experience.
2. A current CV, including contact information for two references.
3. Transcripts (if applicable).

The College of Science seeks a diverse and inclusive workforce and is committed to equality of opportunity. We welcome applications from all and recruit on the basis of merit, regardless of age, race, gender, religion, marital status and family responsibilities, or disability.

We regret to inform that only shortlisted candidates will be notified.

Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore

The School of Biological Sciences (SBS), part of the College of Science, was established in 2002 with a mission to advance biological and biomedical sciences. At SBS, our research spans various areas, including infectious diseases, immunology, neurodegenerative diseases, telomere biology, and genome function. Over the years, SBS has attracted talented individuals from around the world and Singapore to join as scientific leaders and researchers.

Position Available: Research Fellow

Join the laboratory of Lei Lu at the School of Biological Sciences, where we are seeking a motivated and talented Research Fellow to contribute to an exciting project focused on the endocytic trafficking of lipid nanoparticles.

Lipid nanoparticles (LNPs) have gained global attention, especially with their approval for mRNA vaccine delivery during the COVID-19 pandemic, saving millions of lives worldwide. Beyond vaccines, LNPs hold immense potential as delivery vehicles for various therapeutic nucleic acids, offering promising treatment strategies for many diseases. Despite their enormous success, the intracellular transport of LNPs — how they move within mammalian cells and deliver their nucleic acid payloads — remains poorly understood.

As part of our team, the candidate will use advanced light microscopy to explore and elucidate the molecular and cellular mechanisms governing the endocytic trafficking and intracellular delivery of LNPs. This project aims to deepen our understanding of these mechanisms, contributing to the optimization of LNP-based therapies.

Job Description

• Conduct cutting-edge research using high-resolution light microscopy to study LNP trafficking.
• Investigate endocytic pathways and payload delivery molecular mechanisms.
• Collaborate with a multidisciplinary team to advance the field of nanoparticle-based therapeutics.
• Perform any other duties as assigned.

Job Requirements

• PhD in cell biology or related fields, with a focus on membrane trafficking.
• Experience in light microscopy.
• Strong written and verbal communication skills in English - essential for data analysis and communication with stakeholders
• Strong publication record.
• Entry-level candidates are welcome to apply.

The College of Science seeks a diverse and inclusive workforce and is committed to equality of opportunity. We welcome applications from all and recruit on the basis of merit, regardless of age, race, gender, religion, marital status and family responsibilities, or disability.

Interested applicants are invited to apply directly at our NTU Career Portal .

We regret that only shortlisted candidates will be notified.

SIBER SRTT PI position in Computational biology or Systems biology for initially 3 years with a possibility to extend the appointment for an additional 2 years.

A*STAR Strategic Research and Translational Thrusts (SRTTs) are mission-focused programmes in strategic and emerging areas that are cross-disciplinary and of wider strategic interest to A*STAR and Singapore. Set up to address ambitious technological challenges towards impactful outcomes, each SRTT is led by a Programme Director (PD) and is centrally facilitated and supported by A*STAR HQ.

The Singapore Integrative Biosystems & Engineering Research (SIBER) SRTT harnesses synthetic biology capabilities to aid the sustainable transformation of Singapore’s Energy & Chemicals sector with the aim to expand to other sectors. It will create a synthetic biology platform initially for sustainable chemicals and fuels, powered by a unique organism library utilising the biodiversity of Singapore. SIBER’s vision is to be a premier hub in industrial biotechnology innovation for the energy / chemicals as well as other sectors, empowering Singapore to seize opportunities in the future bioeconomy.

We are looking for a PI (senior research fellow or senior principal scientist) with expertise in computational biology or systems biology to join our laboratory in A*STAR SIBER SRTT.

Job Description:

• Lead, design and perform the development and application of state-of-the-art computational tools to direct and inform the microbial strain engineering and metabolic engineering activities of the SIBER SRTT experimental team to produce high-value chemicals in microbial cell factories. This includes, for example, computational approaches to genome mining and retro(bio)synthesis, metabolic pathway modelling and optimisation, protein structure design for novel and improved biochemical functionalities, and the analysis of omics profiles of engineered strains to drive further iterations of the design cycle. All of these should be empowered by the latest advances in artificial intelligence and machine learning (AI/ML) where appropriate.
• Develop applied research, translational and commercialisation strategies, in coordination with the SRTT leadership team.
• Work closely with the other SIBER SRTT team members across disciplines
• Apply for individual research grants as part of career development and apply proactively for research proposals.
• Present findings at seminars, meetings and national / international conferences
• Write manuscripts for publication.
• Contribute to mentorship of PDRAs, students, interns and technicians in the laboratory
• Be an excellent communicator and team player.
• Build and maintain strong relationships with local and international research network.

Requirements:

• PhD in Computational Biology, Systems Biology, Bioinformatics, Cheminformatics, or a related field.
• At least more than 8 years of postdoc experience or independent research experience and leading a research team.
• Strong background in current developments in computational biology and systems biology, including relevant aspects of AI/ML, with demonstrated capability for independently developing and applying state-of-the-art tools for concrete biological applications at the cutting edge of the field.
• Extensive understanding of the key concepts and techniques of synthetic biology / engineering biology, molecular biology, biochemistry, chemical engineering, and process engineering.
• Track record of peer-reviewed scientific publications with at least five first-authored or last-authored papers in internationally recognised journals.
• Dedication, motivation, creativity and passion for scientific research and continuous learning.
• Exceptional analytical, experimental design, technical and problem-solving skills.
• Proficiency in communication, writing and editing scientific documents.
• Demonstrated ability to work independently as well as collaboratively and efficiently in an interdisciplinary team.
• Strong supervisory skills.
• A strong interest in the translational and applied aspects of research, including collaborations with industrial partners.
• Experience in omics technologies, HTP automation facilities, data analysis using various software, state-of-art med-scale fermenters or scale-up fermenters and programming will be a plus.

We offer:

• A well-funded laboratory supported by A*STAR, the National Research Foundation (NRF) and industry to pursue a combination of exciting projects and your scientific interests.
• A nurturing, supportive and stimulating environment with close mentorship to develop your scientific career.
• Access to state-of-the-art technologies, scientific resources, core facilities and infrastructure housed within A*STAR to facilitate your research work.
• Access to collaborations with industrial partners to translate research findings to commercial applications and societal impact.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.