57 Manufacturing Team Lead jobs in Singapore

The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.

Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.

Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.

Esco Aster.

One World Biosolutions for One Health.

Who we’re looking for

Physical / Mental Requirements / Work Environment:

• Strong leadership and communication skills.
• Ability to stay focused under pressure and adapt proactively.
• Critical thinker with a systematic and meticulous approach.
• Curious and self-motivated to stay updated on cell/gene therapy and emerging technologies.
• Committed to safety, quality, compliance, and timely delivery.
• Cleanroom and GMP manufacturing settings.
• Requires standing for long periods, working with sterile systems, and wearing full gowning/PPE.
• May engage in overtime during campaign activities or urgent troubleshooting.

The Scope

To lead and manage the successful technology transfer, manufacturing execution, and commercial readiness of cell and gene therapy products in a cGMP environment, ensuring compliance, efficiency, and delivery excellence throughout the product lifecycle.

Primary work location: Ayer Rajah Crescent, Singapore

Job Responsibilities

• Lead cross-functional biotechnicians and act as the bridge between process development and manufacturing.
• Collaborate with internal/external stakeholders including QA, QC, MSAT, and commercial teams.
• Serve as Manufacturing Subject Matter Expert (SME) during audits, inspections, and due diligence.
• Manage end-to-end technology transfers (internal and external).
• Involve in commissioning, qualification (C&Q) activities.
• Oversee execution of Process Performance Qualification (PPQ), Aseptic Process Simulations (APS), and engineering/pilot runs.
• Oversee cell culture, purification, and fill-finish operations in a single-use, aseptic, cGMP facility.
• Ensure readiness of raw materials, equipment, and team for autologous/allogeneic campaigns.
• Monitor, document, and troubleshoot manufacturing activities, ensuring compliance with SOPs and regulatory requirements.
• Author, review, and manage cGMP documentation: SOPs, batch records, risk assessments, protocols, etc.
• Lead manufacturing change control, deviation investigations and implement CAPAs.
• Lead the implementation of electronic batch records.
• Potentially leading a small team.
• Undertake other tasks as assigned by the management based on project needs.

Requirements

• Minimum Bachelor’s Degree in Biotechnology related disciplines, Chemical Engineering, Pharmaceutical Science or relevant discipline with 2 years or more experience in a cGMP/aseptic environment in biologics or cell and gene therapy.
• Minimum of 4-6 years in cGMP Biologics or cell and gene therapy manufacturing with relevant industry knowledge, hands on equipment experience and technical expertise.
• Strong knowledge of cGMP practices and global regulatory requirements such as USFDA GMP, EU GMP, HSA GMP and PIC/S GMP.
• In-depth knowledge of the drug development process and commercialization pathways.
• Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).
• Able to work independently and task oriented in a dynamic environment.
• Strong team player with a strong set of interpersonal skills.
• Excellent written and verbal communication skills.
• Experience in bringing cell and gene therapy products through clinical development to market is an added advantage.
• Proven track record in regulatory strategy and interactions is an added advantage.
• Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).
• Able to work independently and task oriented in a dynamic environment.
• Strong team player with a strong set of interpersonal skills.
• Excellent written and verbal communication skills.

Apply now by submitting a Cover Letter and CV to .

Job Title: CNC Machinist Supervisor

Are you a skilled professional looking for a challenging role in precision manufacturing? We are seeking a highly motivated and experienced CNC Machinist Supervisor to join our team.

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• As a CNC Machinist Supervisor, you will be responsible for leading a team of machinists and ensuring the production of high-quality parts on time. You will oversee the operation of CNC machines, manage inventory, and maintain a safe and efficient work environment.
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• You will be expected to have excellent leadership and communication skills, as well as the ability to multitask and prioritize tasks effectively. A strong understanding of CNC programming and machining principles is essential.
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• Key responsibilities include:
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1. Leading a team of machinists and overseeing daily operations;
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2. Managing inventory and ordering supplies as needed;
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3. Maintaining a clean and organized workspace;
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4. Ensuring compliance with safety regulations and company policies;
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5. Collaborating with other departments to achieve business objectives;
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6. Developing and implementing process improvements;
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7. Conducting regular quality control checks and identifying areas for improvement.
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8. Required qualifications include:
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• A minimum 5 years' experience in precision manufacturing;
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• Familiarity with automated and smart manufacturing processes;
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• Strong leadership and communication skills;
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• Ability to work independently and collaboratively as part of a team;
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• Excellent problem-solving and analytical skills;
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• Proficiency in CNC programming and machining principles;
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• Valid certification in machine maintenance or related field (an asset).
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• Benefits of this role include:
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• Competitive salary range $4500-$6000 per month;
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• Opportunities for career advancement and professional growth;
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• Collaborative and dynamic work environment;
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• Comprehensive training and support program;
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• Flexible working hours and opportunities for remote work.
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• This is an exciting opportunity to take on new challenges and develop your skills and expertise in precision manufacturing. If you are a motivated and experienced professional looking for a rewarding career, please apply today.
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• Keyword: Manufacturing
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We are seeking a highly skilled and experienced Production Supervisor to join our team. As a key member of our operations department, you will be responsible for leading and managing the production process from start to finish.

The ideal candidate will have a strong background in engineering or chemistry, with a minimum of 3-5 years of experience in a manufacturing environment. You will be expected to possess excellent leadership and communication skills, as well as the ability to work independently and make objective decisions.

Your key responsibilities will include:

• Managing daily production schedules and inventory levels
• Collaborating with inter-department teams to ensure smooth operation
• Creating and maintaining accurate records in SAP systems
• Updating ISO documentation and recording audit processes

To succeed in this role, you will need to have:

• Strong problem-solving and analytical skills
• Excellent communication and interpersonal skills
• Ability to prioritize tasks and manage time effectively
• Proficiency in SAP systems and chemical knowledge

If you are a motivated and detail-oriented individual with a passion for manufacturing, we encourage you to apply for this exciting opportunity. Don't miss out on the chance to take your career to the next level!

This role involves overseeing daily manufacturing of products, managing production schedules and ensuring proper storage conditions.

• Oversee daily manufacturing operations to meet production targets
• Manage production schedules to ensure timely delivery of products
• Monitor production efficiency and implement lean manufacturing principles
• Supervise production staff to optimize productivity
• Ensure compliance with food safety regulations

• Lean manufacturing
• Quality control
• Food safety management
• Operations management
• Problem solving

This is a challenging role that requires strong leadership and problem-solving skills. If you have experience in manufacturing operations and are looking for a new challenge, this could be the perfect opportunity for you.

Company Overview

LionsBot is an international robotics scaleup dedicated to transforming the cleaning and facility services industry. We value ingenuity, problem-solving, adaptability, and an entrepreneurial spirit. As we continue expanding globally, we seek a dynamic Manufacturing Engineer Lead to manage a team of engineers to take charge of all the improvements in the Production Floor. The candidate ensures we have operational excellence and a World Class Assembly floor. Deliver top quality robots to meet sales orders and maintain the quality our customers expect.

Roles & Responsibilities

• Ensure safety compliance through audits and training.
• Ability to lead and motivate a team of assemblers, including Conduct Training / Coaching to Leaders & Assemblers to improve performance
• Own KPI such as Safety, FPY, Continuous Improvement etc.
• Write SOP and Implement Self Inspection procedures.
• Identify process improvements and collaborate with management to enhance productivity and reduce waste and prevent Human errors.
• Ability to analyse problems, identify root causes, and implement corrective actions promptly.
• Ability to prioritize tasks, manage time, and meet deadlines.
• Optimize workflow and lead staff training, fostering a positive work environment.
• Maintain training / Rework records including quality issues.
• Conduct performance evaluations and provide constructive feedback.
• Ensure good discipline and housekeeping in the line.

Requirements & Qualifications

• Minimum Degree in Engineering, Manufacturing or a related field preferred; relevant work experience may be considered in lieu of a degree.
• A minimum of 3-5 years of experience in a Manufacturing Engineer role, preferably in a manufacturing environment.
• Strong background in Engineering.
• Excellent problem-solving abilities and a proactive approach to challenges.
• Six Sigma Green Belt and above.
• Candidate must be highly motivated, be able to work independently as well as in a team and have good organizational and oral and written communication skills.
• Familiarity with production management software (ERP & MES) and Root Cause Analysis methodologies.
• Excellent communication and interpersonal skills, both written and verbal.

If you have a passion for driving meaningful operational improvements, excel at analytical problem-solving, and thrive in a dynamic scaleup atmosphere, we invite you to join LionsBot and help shape the future of robotics innovation.

About the role:
The Manufacturing Operations V role is responsible for managing and performing work associated with converting raw materials and components into finished goods. This includes general production manufacturing work, assembling finished components, process manufacturing batches, setting up and operating machine tools, surface finishing, and packaging materials or finished goods. This role supports Takeda's mission by ensuring high-quality production processes and adherence to safety and regulatory standards.

How you will contribute:
* Manage personal training plan to enhance knowledge, skills, and capabilities
* Troubleshoot process and equipment problems in a timely manner to minimize manufacturing downtime
* Conduct safety Gemba's and provide coaching daily to ensure technicians are adhering to proper ergonomic techniques
* Support all local manufacturing operations
* Operate general production equipment (such as Filling, Inspection, & Packaging equipment)
* Oversee the hands-on execution of all activities in the production area
* Participate in departmental projects and quality working teams

Skills and qualifications:
* Applies advanced lean manufacturing techniques, capable of advising others and anticipating future manufacturing requirements.
* Recognized as an expert in environmental health and safety, able to develop strategic safety initiatives and coach others at all levels.
* Advanced ability in product and manufacturing information, capable of applying knowledge in complex situations and guiding others.
* Expert in good manufacturing practices, provides strategic insights and supervises others in the domain.
* Skilled in conducting investigations, recognized for deep expertise and leadership in investigative strategies, coaching others.
* Leads in quality control in complex situations, advising others and making improvement recommendations based on advanced knowledge.
* Manages workflows independently, understands optimization strategies, and requires minimal guidance.
* Performs advanced troubleshooting, guiding others through complex problem-solving processes, and recommending improvements.
* Expertly handles the operation and maintenance of production equipment, including in complex situations, providing guidance to others.
* Drives team efforts through advanced understanding of team dynamics, capable of coaching others and improving team processes.
* Excellently manages tasks requiring high attention to detail, independently addresses complex scenarios, and advises others on maintaining precision.
* Independently applies continuous improvement process principles in routine and moderately complex situations with minimal guidance, showing a comprehensive understanding of the concepts and methodologies.

As the most advanced technical operations level within Takeda, you are in a non-supervisory position that calls for a profound understanding of technical processes within one's specialty. You typically hold a high school diploma complemented by extensive relevant working experience and any necessary certifications. You will be expected to anticipate trends, connect disparate information, and coordinate activities that may impact areas outside your immediate remit. In this capacity, you will handle complex assignments that necessitate a unique and specialized set of skills, leading not just the workflow but also ensuring the quality of technical processes. Your autonomous working style within established procedures empowers you to propose process enhancements and sometimes operate without predefined methods, guided by experience and organizational guidelines.

We are seeking a highly skilled professional to fill the role of Operational Excellence Specialist within our organisation. This is an exciting opportunity for a seasoned expert to lead and support strategic projects focused on digital transformation, process optimisation, and cross-functional collaboration.

• Lead and support strategic projects across APAC region, leveraging expertise in digital transformation, analytics, and automation initiatives.
• Coordinate the rollout of Manufacturing Execution Systems (MES) across multiple sites, ensuring seamless integration and efficient operations.
• Share best practices and contribute to regional Gap Assessments, driving continuous improvement and excellence.
• Assist in developing technical training programs and skills matrices, enhancing team capabilities and performance.
• Represent process and quality requirements in infrastructure planning and commissioning for new installations, ensuring compliance and efficiency.
• Monitor internal performance indicators and support improvement efforts, driving organisational growth and success.
• Participate in integrated audits and maturity assessments, maintaining high standards and excellence.
• Collaborate with cross-functional teams across operations, engineering, and supply chain, fostering effective communication and teamwork.

To succeed in this role, you will require:

• A degree in Engineering or Data Science.
• 10 years of experience in a manufacturing environment, preferably within the chemical industry.
• Minimum 3 - 5 years in Continuous Improvement, with hands-on experience in Lean methodologies.
• Proven track record in digitalization and automation projects.
• Lean Six Sigma Green Belt or Continuous Improvement certification is preferred.

If you possess the necessary skills and qualifications, we encourage you to apply for this exciting opportunity.

Company Overview

LionsBot is an international robotics scaleup dedicated to transforming the cleaning and facility services industry. We value ingenuity, problem-solving, adaptability, and an entrepreneurial spirit. As we continue expanding globally, we seek a dynamic Manufacturing Engineer Lead to manage a team of engineers to take charge of all the improvements in the Production Floor. The candidate ensures we have operational excellence and a World Class Assembly floor. Deliver top quality robots to meet sales orders and maintain the quality our customers expect.

Roles & Responsibilities

• Ensure safety compliance through audits and training.
• Ability to lead and motivate a team of assemblers, including Conduct Training / Coaching to Leaders & Assemblers to improve performance
• Own KPI such as Safety, FPY, Continuous Improvement etc.
• Write SOP and Implement Self Inspection procedures.
• Identify process improvements and collaborate with management to enhance productivity and reduce waste and prevent Human errors.
• Ability to analyse problems, identify root causes, and implement corrective actions promptly.
• Ability to prioritize tasks, manage time, and meet deadlines.
• Optimize workflow and lead staff training, fostering a positive work environment.
• Maintain training / Rework records including quality issues.
• Conduct performance evaluations and provide constructive feedback.
• Ensure good discipline and housekeeping in the line.

Requirements & Qualifications

• Minimum Degree in Engineering, Manufacturing or a related field preferred; relevant work experience may be considered in lieu of a degree.
• A minimum of 3-5 years of experience in a Manufacturing Engineer role, preferably in a manufacturing environment.
• Strong background in Engineering.
• Excellent problem-solving abilities and a proactive approach to challenges.
• Six Sigma Green Belt and above.
• Candidate must be highly motivated, be able to work independently as well as in a team and have good organizational and oral and written communication skills.
• Familiarity with production management software (ERP & MES) and Root Cause Analysis methodologies.
• Excellent communication and interpersonal skills, both written and verbal.

If you have a passion for driving meaningful operational improvements, excel at analytical problem-solving, and thrive in a dynamic scaleup atmosphere, we invite you to join LionsBot and help shape the future of robotics innovation.