6 Cell Culture jobs in Singapore

We are seeking an experienced Biotechnologist to collaborate with our team of specialists in the Life Science and Technology sectors.

The ideal candidate will design, validate, and optimize new experimental techniques to ensure the integrity and purity of cell cultures.

• Lead operations involving process control systems and configure protocol handshakes for efficient execution.
• Manage and optimize batch recipe inputs for bioprocess efficiency.
• Execute and optimize chromatography techniques in downstream processing.
• Cross-functionally collaborate to ensure compliance with standard operating procedures and process documentation.
• Contribute to technical workflows and automation strategies.
• Maintain regulatory requirements and Good Manufacturing Practice standards.

Requirements:

• Bachelor's degree in a relevant life science field.
• Minimum 5 years of experience in biotechnology or biopharmaceutical manufacturing.
• Excellent communication skills in English.
• Able to multitask and work in a fast-paced environment with competing priorities.
• Strong interpersonal and communication skills.

• Execute routine cell culture processes (e.g., CLC, bioreactors, or characterization stages)
• Lead multiple projects in your area of expertise, providing oversight to junior scientists within the project teams.
• Efficiently manage personal and team workflows to meet project goals with minimal supervision.
• Demonstrate a history of successfully delivering projects of increasing complexity.
• Document results in alignment with Lonza policies and cGMP requirements as applicable.
• Serve as a department/site Subject Matter Expert (SME) in one or more technical areas aligned with your training.
• Build and maintain a network of contacts on-site and globally to support project objectives.
• Provide general lab support, including housekeeping, equipment maintenance, and inventory management, while driving operational efficiency initiatives.
• Troubleshoot equipment and scientific issues effectively.
• Actively participate in internal and customer project teams, including direct communication and external presentations.
• Prepare reports and protocols suitable for management review and review communications from junior team members.
• Train team members in lab procedures and provide scientific guidance.
• Collaborate with project managers and business unit teams to develop scopes of work and amendments.
• Perform additional duties as assigned by management.

• Degree or PhD in Biological Science/Engineering relevant to the area of expertise.
• 5-10 years of laboratory experience in industry or academia (with a PhD).
• In-depth understanding of the scientific rationale underpinning one or more technical areas in biopharmaceutical development.
• Knowledge of cGMP regulations.
• Exceptional problem-solving and analytical abilities paired with strong communication skills.

• Execute routine cell culture processes (e.g., CLC, bioreactors, or characterization stages)
• Lead multiple projects in your area of expertise, providing oversight to junior scientists within the project teams.
• Efficiently manage personal and team workflows to meet project goals with minimal supervision.
• Demonstrate a history of successfully delivering projects of increasing complexity.
• Document results in alignment with Lonza policies and cGMP requirements as applicable.
• Serve as a department/site Subject Matter Expert (SME) in one or more technical areas aligned with your training.
• Build and maintain a network of contacts on-site and globally to support project objectives.
• Provide general lab support, including housekeeping, equipment maintenance, and inventory management, while driving operational efficiency initiatives.
• Troubleshoot equipment and scientific issues effectively.
• Actively participate in internal and customer project teams, including direct communication and external presentations.
• Prepare reports and protocols suitable for management review and review communications from junior team members.
• Train team members in lab procedures and provide scientific guidance.
• Collaborate with project managers and business unit teams to develop scopes of work and amendments.
• Perform additional duties as assigned by management.

• Degree or PhD in Biological Science/Engineering relevant to the area of expertise.
• 5-10 years of laboratory experience in industry or academia (with a PhD).
• In-depth understanding of the scientific rationale underpinning one or more technical areas in biopharmaceutical development.
• Knowledge of cGMP regulations.
• Exceptional problem-solving and analytical abilities paired with strong communication skills.

Senior/Research Engineer (hiPSC Cell Culture)
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SMART CAMP (Critical Analytics for Manufacturing Personalized-Medicine) is an interdisciplinary research programme in Singapore (CREATE international research campus and innovation hub) and at the Massachusetts Institute of Technology (MIT). SMART CAMP addresses key technology bottlenecks in cell therapy manufacturing: (i) critical quality attributes (CQA) of safe, effective cell therapy products; and (ii) integrated process analytics to monitor and modulate those attributes. Our efforts are focused on expansion of cGMP grade hiPSCs and differentiation to progenitor cells for cell therapy products.
Job Description
The successful candidate will support interdisciplinary projects focused on translating candidate safety Critical Process Parameters (CPPs) to improve the safety of cell therapy products. He/She will work under the supervision of postdoctoral associates in SMART CAMP, with mentorship by principal investigators in Singapore and MIT. The primary activities include routine hiPSC cell culture maintenance and expansion, molecular-based assays according to established protocols, and general lab housekeeping including inventory, SOPs, and risk assessments.
Requirements
Bachelor of Science degree or diploma in a biology-related discipline with minimum 2 years of relevant experience.
Experience in mammalian cell culture is essential.
Experience in molecular and cellular biology techniques such as qPCR, immunofluorescence staining, basic microscopy, and FACS.
Experience in cell manufacturing or using Design of Experiments (DOE) software is advantageous.
Motivated to learn and achieve high consistency and reproducibility in experiments.
Detail-oriented with good organizational, communication, record-keeping, and time management skills.
Seniority level
Associate
Employment type
Full-time
Job function
Engineering, Science, and Other
Industries
Research Services
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The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.

Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.

Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.

Esco Aster.

One World Biosolutions for One Health.

Who we’re looking for

Physical/Mental Requirements/Work Environment

· Ability to read, analyze and interpret scientific data and publications.

· Ability to author or review protocols, technical reports, and technology transfer documents.

· Ability to author or review standard operating procedures and other related documents.

· Ability to define problems, collect data, establish facts, and draw conclusions.

· Repetitive motions due to certain laboratory techniques.

· Ability to adapt and keep up with rapid changes in a fluid and dynamic environment as this is a rapidly evolving space.

The Scope

You will be part of Esco Aster’s Genetically Modified Cell Therapy (GMC) team and contribute to the company’s CDMO mission and objectives. You will carry out process development and analytical development activities in support of drug substance and product manufacturing and testing. Your work will require close collaboration with the process development scientists and manufacturing team.

Reporting to: Head of Scientific & Sales Operations

Responsibilities

· Participate in multiple projects in the area of cell and gene therapy for process development and analytical development from small to large scale.

· Perform lab work based on the project schedule and assigned tasks from supervisors in a time efficient manner.

· Perform hands-on daily laboratory work including but not limited to primary cell culture (stem cells, immune cells, tumour cells etc.), cell-based assays (cell imaging, flow cytometry assays, killing assays etc.) and other molecular assays (ELISA, metabolite analysis etc.)

· Carry out experiment data collection, record and analysis for projects per request.

· Be involved and contribute to creation of protocols and technical reports.

· Assist in lab duties and administrative work including procurement, record keeping, maintenance of lab equipment etc.

· Exercise scientific creativity and independent thought in research & process development.

· Perform tasks in accordance with applicable regulations and site safety requirements.

· Undertake tasks assigned by leaders as and when appropriate.

Requirements

· Degree in Life Sciences or related disciplines.

· Minimum 2 years work experience in a science laboratory.

· Experience with good laboratory practices (GLP) will be an advantage.

· Experience in cell culture, aseptic techniques and analytical method development will be an advantage.

· Experience in stem cell culture / immune cell culture would be preferred.

· Experienced with bioprocess scale-up would be an advantage.

· Ability to plan and perform experiments in an interdisciplinary environment independently and efficiently.

· Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).

· Able to work independently, self-starter, self-motivated and task oriented.

· Excellent written and verbal communication skills.

· Strong team player, develop positive relationship with a strong set of interpersonal skills.

· During the start-up phase of the team/facility, be willing to take on expanded role to set up workflow/processes as needed.

Apply now by submitting a Cover Letter and CV to .