10 Cell Culture jobs in Singapore

The primary function of this position is to oversee the daily operations of a cell culture facility and shared equipment.

Key responsibilities include conducting risk assessments, safety inductions, waste disposal, logistical support, procurement, teaching modules, planning, and management support.

In addition, the ideal candidate will be responsible for drafting, reviewing, and implementing standard operating procedures (SOPs) for safety and maintenance processes.

This role also requires ensuring compliance with institutional regulatory requirements and best practices, as well as maintaining accurate records of fixed assets, planning events, managing computing resources, and other tasks.

Preferred qualifications include a bachelor's degree in science, engineering, or a related field, and 2-3 years of relevant working experience.

• Bachelor's degree in science, engineering, or related fields
• Strong organizational skills and proficiency in Microsoft Office

A career at our organization offers opportunities for professional growth and development in a dynamic work environment.

• Perform hands-on laboratory work in the cell line and upstream process development team contributing to the development of processes suitable for technology

Responsibilities

• Cultivate and express antibody intermediates in an industrial-scale cell culture platform using single-use technologies.

● Perform vial thawing, cell expansion and passage, cell culture, and harvest manufacturing in drug substance facilities in accordance with GMP requirements.

● Operate equipment and appliances following the guidance of SOPs and relevant documents.

● Prepare relevant documents, such as production batch records, SOPs, and validation reports.

● Communicate and resolve any inconsistencies and/or anomalies in production operations.

● Monitor processes, including real-time review of process parameters and process data/trends.

● Ensure that the manufacturing operations for drug substances comply with quality and safety regulations.

● Perform other tasks assigned by leadership.

● Participate in shift production as required and ensure that shift production meets SOP requirements.

Requirements

● Diploma or higher qualification in Biological, Chemical, Pharmaceutical Engineering, or other related specialties; candidates with equivalent work experience will also be considered.

● Possess thorough scientific reasoning and methodical work habits, with strong execution and planning abilities.

● Ability to adapt to a GMP cleanroom environment, including the requirement to wear dust-free clothing, masks, and goggles.

● Possess good communication ability and comprehension ability.

● Display a good working attitude, strong work ethic, and willingness to follow leadership directives.

● Be open to accepting temporary work assignments, including overtime on weekends or weekdays, and other roles as required.

Career Development

● Comprehensive in-house training program (E-learning / OJT / Mentorship)

● Dual career development tracks – Professional & Managerial Tracks

● Opportunity for internal job rotation / Cross-BU transfer / Cross-country assignment

● Cross cultural learning

● GMP greenfield start-up experience

Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that's the kind of work we want to be part of.

As a Biotechnologist at Lonza Mammalian business, you'll be part of our globally recognized network, driving the production of mammalian cell culture and treatments.

Join our best-in-class high performance Integrated Biologics team at our Tuas site in Singapore to gain unparalleled exposure to cutting-edge biotechnology and innovation and make a difference from day one. Learn new skills and capabilities. Grow your career with us in manufacturing therapeutic proteins under cGMP conditions. Find out more about what a life at Lonza in Singapore could look like for you by watching this short video.

What you'll get:

• An agile career and dynamic working culture.
• An inclusive and ethical workplace.
• Compensation programs that recognize high performance.
• Daily company bus from the MRT location near your home to and from the Tuas site.
• Fully paid medical insurance, with the option to enroll family members at partially subsidized premiums.
• Shift allowances.

The full list of our global benefits can be also found on

What you'll do:

• Perform GMP manufacturing operations, equipment handling, and troubleshooting.
• Maintain facility and lab standards through sanitization and 6S housekeeping.
• Apply aseptic techniques for material and cell culture handling.
• Operate bioreactors, monitoring pH/DO, CO2/O2, and cell performance.
• Execute chromatography, ultrafiltration, and pH/conductivity adjustments.
• Utilize process control systems (UNICORN, DeltaV) and documentation (SOPs, logbooks, BRs).
• Handle single-use technologies and sample submissions via LIMS.
• Prepare customer-specific solutions and set up equipment for operations (CIPs, buffer transfer).
• Plan and execute CIPs (downstream), ensuring correct pathways and configurations.

What we're looking for:

• Degree or diploma in a related Science/Engineering field.
• Knowledge of Biopharmaceutical processing is an added asset.
• Relevant work experience in a similar manufacturing industry or cleanroom environment preferred.
• Knowledge of cGMP applications.
• Positive team oriented demeanor.
• Strong communication and interpersonal skills.
• Willing to perform a rotating 12-hour shift pattern.

Every day, Lonza's products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that's the kind of work we want to be part of.

As a Biotechnologist at Lonza Mammalian business, you'll be part of our globally recognized network, driving the production of mammalian cell culture and treatments.

Join our best-in-class high performance Integrated Biologics team at our Tuas site in Singapore to gain unparalleled exposure to cutting-edge biotechnology and innovation. Learn new skills and capabilities. Grow your career with us in manufacturing therapeutic proteins under cGMP conditions. Find out more about what a life at Lonza in Singapore could look like for you by watching this short video.

What you'll get:

• An agile career and dynamic working culture.
• An inclusive and ethical workplace.
• Compensation programs that recognize high performance.
• Daily company bus from the MRT location near your home to and from the Tuas site.
• Fully paid medical insurance, with the option to enroll family members at partially subsidized premiums.
• Shift allowances. The full list of our global benefits can be also found on

What you'll do:

• Perform GMP manufacturing operations, equipment handling, and troubleshooting.
• Maintain facility and lab standards through sanitization and 6S housekeeping.
• Apply aseptic techniques for material handling and cell subculture.
• Operate bioreactors, monitoring pH/DO, CO2/O2, and cell performance.
• Execute chromatography, filtration, and pH/conductivity adjustments.
• Utilize process control systems (UNICORN, DeltaV) and documentation (SOPs, logbooks, BRs).
• Handle single-use technologies and sample submissions via LIMS.
• Prepare customer-specific solutions and set up equipment for operations (CIPs, buffer/media transfer).
• Plan and execute CIPs, ensuring correct pathways and configurations.

What we're looking for:

• Degree or diploma in a related Science/Engineering field.
• Knowledge of Biopharmaceutical processing is an added asset.
• Relevant work experience in a similar manufacturing industry or cleanroom environment preferred.
• Knowledge of cGMP applications.
• Positive team-oriented demeanor.
• Strong communication and interpersonal skills.
• Willing to perform a rotating 12-hour shift pattern.

Every day, Lonza's products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Responsibilities
Cultivate and express antibody intermediates in an industrial-scale cell culture platform using single-use technologies.
Perform vial thawing, cell expansion and passage, cell culture, and harvest manufacturing in drug substance facilities in accordance with GMP requirements.
Operate equipment and appliances following the guidance of SOPs and relevant documents.
Prepare relevant documents, such as production batch records, SOPs, and validation reports.
Communicate and resolve any inconsistencies and/or anomalies in production operations.
Monitor processes, including real-time review of process parameters and process data/trends.
Ensure that the manufacturing operations for drug substances comply with quality and safety regulations.
Perform other tasks assigned by leadership.
Participate in shift production as required and ensure that shift production meets SOP requirements.
Requirements
Diploma or higher qualification in Biological, Chemical, Pharmaceutical Engineering, or other related specialties; candidates with equivalent work experience will also be considered.
Possess thorough scientific reasoning and methodical work habits, with strong execution and planning abilities.
Ability to adapt to a GMP cleanroom environment, including the requirement to wear dust-free clothing, masks, and goggles.
Possess good communication ability and comprehension ability.
Display a good working attitude, strong work ethic, and willingness to follow leadership directives.
Be open to accepting temporary work assignments, including overtime on weekends or weekdays, and other roles as required.
Career Development
Comprehensive in-house training program (E-learning / OJT / Mentorship)
Dual career development tracks – Professional & Managerial Tracks
Opportunity for internal job rotation / Cross-BU transfer / Cross-country assignment
Cross cultural learning
GMP greenfield start-up experience
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Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that's the kind of work we want to be part of.

As a Biotechnologist at Lonza Mammalian business, you'll be part of our globally recognized network, driving the production of mammalian cell culture and treatments.

Join our best-in-class high performance Integrated Biologics team at our Tuas site in Singapore to gain unparalleled exposure to cutting-edge biotechnology and innovation. Learn new skills and capabilities. Grow your career with us in manufacturing therapeutic proteins under cGMP conditions. Find out more about what a life at Lonza in Singapore could look like for you by watching this short video.

What you'll get:

• An agile career and dynamic working culture.
• An inclusive and ethical workplace.
• Compensation programs that recognize high performance.
• Daily company bus from the MRT location near your home to and from the Tuas site.
• Fully paid medical insurance, with the option to enroll family members at partially subsidized premiums.
• Shift allowances. The full list of our global benefits can be also found on

What you'll do:

• Perform GMP manufacturing operations, equipment handling, and troubleshooting.
• Maintain facility and lab standards through sanitization and 6S housekeeping.
• Apply aseptic techniques for material handling and cell subculture.
• Operate bioreactors, monitoring pH/DO, CO2/O2, and cell performance.
• Execute chromatography, filtration, and pH/conductivity adjustments.
• Utilize process control systems (UNICORN, DeltaV) and documentation (SOPs, logbooks, BRs).
• Handle single-use technologies and sample submissions via LIMS.
• Prepare customer-specific solutions and set up equipment for operations (CIPs, buffer/media transfer).
• Plan and execute CIPs, ensuring correct pathways and configurations.

What we're looking for:

• Degree or diploma in a related Science/Engineering field.
• Knowledge of Biopharmaceutical processing is an added asset.
• Relevant work experience in a similar manufacturing industry or cleanroom environment preferred.
• Knowledge of cGMP applications.
• Positive team-oriented demeanor.
• Strong communication and interpersonal skills.
• Willing to perform a rotating 12-hour shift pattern.

Every day, Lonza's products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.

Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.

Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.

Esco Aster.

One World Biosolutions for One Health.

Who we’re looking for

Physical/Mental Requirements/Work Environment

· Ability to read, analyze and interpret scientific data and publications.

· Ability to author or review protocols, technical reports, and technology transfer documents.

· Ability to author or review standard operating procedures and other related documents.

· Ability to define problems, collect data, establish facts, and draw conclusions.

· Repetitive motions due to certain laboratory techniques.

· Ability to adapt and keep up with rapid changes in a fluid and dynamic environment as this is a rapidly evolving space.

The Scope

You will be part of Esco Aster’s Genetically Modified Cell Therapy (GMC) team and contribute to the company’s CDMO mission and objectives. You will carry out process development and analytical development activities in support of drug substance and product manufacturing and testing. Your work will require close collaboration with the process development scientists and manufacturing team.

Reporting to: Head of Scientific & Sales Operations

Responsibilities

· Participate in multiple projects in the area of cell and gene therapy for process development and analytical development from small to large scale.

· Perform lab work based on the project schedule and assigned tasks from supervisors in a time efficient manner.

· Perform hands-on daily laboratory work including but not limited to primary cell culture (stem cells, immune cells, tumour cells etc.), cell-based assays (cell imaging, flow cytometry assays, killing assays etc.) and other molecular assays (ELISA, metabolite analysis etc.)

· Carry out experiment data collection, record and analysis for projects per request.

· Be involved and contribute to creation of protocols and technical reports.

· Assist in lab duties and administrative work including procurement, record keeping, maintenance of lab equipment etc.

· Exercise scientific creativity and independent thought in research & process development.

· Perform tasks in accordance with applicable regulations and site safety requirements.

· Undertake tasks assigned by leaders as and when appropriate.

Requirements

· Degree in Life Sciences or related disciplines.

· Minimum 2 years work experience in a science laboratory.

· Experience with good laboratory practices (GLP) will be an advantage.

· Experience in cell culture, aseptic techniques and analytical method development will be an advantage.

· Experience in stem cell culture / immune cell culture would be preferred.

· Experienced with bioprocess scale-up would be an advantage.

· Ability to plan and perform experiments in an interdisciplinary environment independently and efficiently.

· Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).

· Able to work independently, self-starter, self-motivated and task oriented.

· Excellent written and verbal communication skills.

· Strong team player, develop positive relationship with a strong set of interpersonal skills.

· During the start-up phase of the team/facility, be willing to take on expanded role to set up workflow/processes as needed.

Apply now by submitting a Cover Letter and CV to .

Senior Research Fellow, Advanced Human Cell (Respiratory) Culture (LKCMedicine) page is loaded# Senior Research Fellow, Advanced Human Cell (Respiratory) Culture (LKCMedicine)locations:
NTU Novena Campus, Singaporetime type:
Full timeposted on:
Posted Todayjob requisition id:
R The Lee Kong Chian School of Medicine (LKCMedicine) trains doctors who put patients at the centre of their exemplary care. The School, which offers both undergraduate and graduate programmes, is named after local philanthropist Tan Sri Dato Lee Kong Chian. Established in 2010 by Nanyang Technological University, Singapore, in partnership with Imperial College London, LKCMedicine aims to be a model for innovative medical education and a centre for transformative research. The School’s primary clinical partner is the National Healthcare Group, a leader in public healthcare recognised for the quality of its medical expertise, facilities and teaching. The School is transitioning to an NTU medical school ahead of the 2028 successful conclusion of the NTU-Imperial partnership to set up a Joint Medical School. In August 2024, we welcomed our first intake of the NTU MBBS programme, that has been recently enhanced to include themes like precision medicine and Artificial Intelligence (AI) in healthcare, with an expanded scope in the medical humanities. Graduates from the five-year undergraduate medical degree programme will have a strong understanding of the scientific basis of medicine, with an emphasis on technology, data science and the humanities.Research in the Chotirmall Lab centres on translational respiratory science, aiming to improve patient care through a deeper scientific understanding of disease. The group focuses on clinically significant areas affecting Singaporean and Asian populations, particularly chronic inflammatory lung diseases like bronchiectasis, COPD, and severe asthma. By combining genomic, molecular, and clinical approaches, the lab investigates disease mechanisms and geographic variation to support personalized treatment strategies. A key area of interest is infectious respiratory disease and the pulmonary microbiome, especially the roles of Aspergillus fumigatus and Pseudomonas aeruginosa in chronic lung conditions. The lab also explores environmental impacts on infection and has developed novel data science tools for microbiome integration and patient risk stratification. For more details, please viewWe are currently recruiting a **Senior Research Fellow** with expertise in advanced human cell culture, focusing on airway epithelial models. The key objective of this role is to support the development and implementation of a national biorepository of respiratory-derived cell cultures, with the overarching aim of enhancing pandemic preparedness. This includes contributing to the establishment, characterization, and maintenance of a diverse and well-documented repository of human respiratory cell models that can be rapidly accessed for research, diagnostic, and therapeutic response during emerging infectious disease outbreaks.**Key Responsibilities:*** Lead and maintain hNEC-ALI cultures from human clinical samples, ensuring high-quality differentiation and reproducibility.* Establish and optimize airway or lung-derived organoid models for experimental use.* Process and handle human biospecimens (e.g., nasal brushes, tissue biopsies) in compliance with institutional biosafety and ethical standards.* Design and perform functional assays (e.g., TEER, immunofluorescence, gene expression analysis) on ALI and organoid systems.* Collaborate with molecular biology and bioinformatics teams for downstream analysis (e.g., transcriptomics, microbiome interaction studies).* Maintain accurate experimental records and contribute to SOP development and optimization.* Supervise and mentor junior staff or research assistants as needed.* Contribute to manuscript preparation, grant applications, and research presentations.* Manage data organization, storage, and documentation to ensure reproducibility and compliance with data governance policies.* Assist in lab administration tasks to ensure smooth research operations.* Provide leadership in strategy development to guide research priorities. Collaborate with multidisciplinary teams, including researchers, clinicians, and external partners, to advance research projects.* Maintain a strong record of publication output in peer-reviewed journals, and present research findings at national and international conferences, seminars, and workshops.* Write grant proposals and contribute to securing funding for ongoing and future research projects.* Mentor junior staff to build capacity and foster professional growth.**Key Competencies and Requirements:*** PhD in Cell Biology, Biomedical Science, or related field, with >3 years of relevant postdoctoral or equivalent experience.* Proven expertise in human primary airway epithelial cell culture and/or organoid technology.* Strong hands-on experience in hNEC isolation, differentiation, and maintenance at air-liquid interface.* Experience in 3D organoid culture techniques and manipulation.* Proficiency in microscopy (including IF/IHC), qPCR, ELISA, and functional assays for epithelial biology.* Familiarity with ethical and biosafety handling of human clinical samples.* Experience in respiratory infectious disease models and host–microbiome interaction studies is highly preferable.* Highly organized, detail-oriented, and capable of multitasking across projects.* Excellent written and verbal communication skills.* Strong collaborative mindset and ability to work in a team-based research environment.* Leadership qualities with mentoring or supervisory experience preferred.We regret to inform that only shortlisted candidates will be notified.Hiring Institution: LKCNTU is also home to world-class autonomous institutes – the National Institute of Education, S Rajaratnam School of International Studies, Earth Observatory of Singapore, and Singapore Centre for Environmental Life Sciences Engineering – and various leading research centres such as the Nanyang Environment & Water Research Institute (NEWRI) and Energy Research Institute @ NTU ( ).Ranked amongst the world’s top universities by QS, NTU has also been named the world’s top young university for the past seven years. The University’s main campus is frequently listed among the Top 15 most beautiful university campuses in the world and has 57 Green Mark-certified (equivalent to LEED-certified) buildings, of which 95% are certified Green Mark Platinum. Apart from its main campus, NTU also has a campus in Novena, Singapore’s healthcare district.Under the NTU Smart Campus vision, the University harnesses the power of digital technology and tech-enabled solutions to support better learning and living experiences, the discovery of new knowledge, and the sustainability of resources.For more information, visit
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