106 Biology Research jobs in Singapore

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We regret that only shortlisted candidates will be notified.

The Synthetic Biology Translational Research Programme (TRP) at the National University of Singapore Yong Loo Lin School of Medicine is seeking talented postdoctoral or research fellows to join our team.

Synthetic Biology TRP – Research Fellow

The Synthetic Biology Translational Research Programme (TRP) focuses on engineering red blood cells for therapeutic applications, including drug delivery, immune modulation, and gene therapy. We are developing novel erythrocyte-based platforms that leverage the unique properties of RBCs for synthetic biology and biomedical innovation.

We invite applications for a highly motivated Research Fellow (RF) to work closely with the Principal Investigator and a multidisciplinary team. The position is offered on an initial one-year contract, renewable subject to performance and funding. A Ph.D. in cell biology, molecular biology, synthetic biology, or a related field is required.

1. RBC Genomics and TranscriptomicsAnalyze gene expression and genomic regulation of erythroid differentiation.
   Characterize key transcriptional and epigenetic programs governing RBC development and function.
   
2. RBC Engineering and Expression SystemsDevelop workflows for genetic modification of erythroid progenitors and immortalized RBC lines.
   Optimize lentiviral and non-viral gene delivery systems to express therapeutic payloads in RBCs.
   
3. Protein Loading and Display in RBCsEngineer red blood cells to load or surface-display proteins, peptides, or other biologics.
   Evaluate protein stability, localization, and bioactivity post-engineering.
   
4. RBC-based Therapeutic DevelopmentDesign and execute functional assays to assess therapeutic efficacy of engineered RBCs.
   Collaborate on in vivo models to evaluate biodistribution, immune responses, and pharmacodynamics.
   
5. Mentorship & Training
   • Supervise and mentor research assistants, graduate students, and undergraduate interns.
6. Additional Duties
   • Undertake other tasks assigned by the Principal Investigator or project leads as needed.

The applicant should:

• Hold a PhD in Biotechnology, Molecular Biology, Biochemistry, RNA Biology, or a related field.

Essential Qualifications & Attributes

Red Blood Cell Engineering Experience

• Hands-on experience with primary erythroid cultures, immortalized erythroid progenitor cell lines, or ex vivo RBC production systems.
• Skilled in flow cytometry, magnetic separation, and enucleation assays for erythroid lineage tracking and quality control.
• Familiarity with ethical guidelines and biosafety considerations in handling blood-derived materials and genetically modified cells.

Synthetic Biology Skills for RBC Platforms

• Proficiency in genetic construct design, vector engineering, and transgene integration for expression in erythroid cells.
• Experience with protein or nucleic acid loading strategies in mature RBCs or erythroid precursors.
• Competence in troubleshooting gene expression systems and optimizing yield, stability, and functional output of engineered RBCs.

Experimental Design & Execution

- Ability to design and conduct RNA/protein expression analyses, enzymatic assays, and studies of RNA chemical modifications.

Research Excellence

- Strong record of high‑impact, peer‑reviewed international publications.

Professional Qualities

- Independent, highly motivated, and detail‑oriented.

- Effective collaborator in multidisciplinary research environments.

Remuneration will be commensurate to the candidate's qualifications and experience. Informal enquiries are welcome and should be made to

Ms Suhana Sulaiman , at

Formal application: Please submit your application, indicating job reference number and current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of 3 referees). Only shortlisted candidates will be notified.

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Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore

The School of Biological Sciences (SBS), part of the College of Science, was established in 2002 with a mission to advance biological and biomedical sciences. At SBS, our research spans various areas, including infectious diseases, immunology, neurodegenerative diseases, telomere biology, and genome function. Over the years, SBS has attracted talented individuals from around the world and Singapore to join as scientific leaders and researchers.

For more details, please view are seeking a highly motivated Research Fellow to join our dynamic team at the School of Biological Sciences, Nanyang Technological University, Singapore. This role focuses on elucidating the 3D structures of corneal amyloid using advanced structural biology techniques. The successful candidate will contribute to cutting-edge research at the intersection of structural biology and biomedical science, with a particular emphasis on NMR spectroscopy and cryo-electron microscopy (cryo-EM).

Key Responsibilities

• Conduct research on corneal amyloids, including their structural characterization using advanced techniques such as NMR and cryo-EM.
• Develop and refine methodologies to investigate amyloid formation and its role in disease pathology.
• Collaborate with interdisciplinary teams, including clinical and animal model researchers, to advance amyloid research.
• Publish research findings in peer-reviewed journals and contribute to scientific knowledge dissemination.
• Provide mentorship and guidance to post-graduate students and junior researchers.
  
  

• PhD degree in Structural Biology, Biochemistry or related field
• Hands-on experience with NMR spectroscopy and cryo-EM for structural characterization.
• Prior completion of a laboratory animal handling course is highly preferred.
• Strong written and verbal communication skills, with the ability to present research findings effectively.
• Demonstrated ability to work independently, think critically, and develop solutions under tight deadlines.
• Proven ability to collaborate in a dynamic, multidisciplinary research environment.
  
  

• Seniority level Entry level

• Employment type Full-time

• Job function Research, Analyst, and Information Technology
• Industries Higher Education

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Geylang, Central Singapore Community Development Council, Singapore 2 months ago

Boon Lay, West Region, Singapore 23 hours ago

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Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The Synthetic Biology Translational Research Programme (TRP) at the National University of Singapore Yong Loo Lin School of Medicine is seeking talented postdoctoral or research fellows to join our team.

Synthetic Biology TRP – Research Fellow

The Synthetic Biology Translational Research Programme (TRP) focuses on engineering red blood cells for therapeutic applications, including drug delivery, immune modulation, and gene therapy. We are developing novel erythrocyte-based platforms that leverage the unique properties of RBCs for synthetic biology and biomedical innovation.

We invite applications for a highly motivated Research Fellow (RF) to work closely with the Principal Investigator and a multidisciplinary team. The position is offered on an initial one-year contract, renewable subject to performance and funding. A Ph.D. in cell biology, molecular biology, synthetic biology, or a related field is required.

Key Responsibilities

1. RBC Genomics and TranscriptomicsAnalyze gene expression and genomic regulation of erythroid differentiation.
   Characterize key transcriptional and epigenetic programs governing RBC development and function.
   
   RBC Engineering and Expression SystemsDevelop workflows for genetic modification of erythroid progenitors and immortalized RBC lines.
   Optimize lentiviral and non-viral gene delivery systems to express therapeutic payloads in RBCs.
   
   Protein Loading and Display in RBCsEngineer red blood cells to load or surface-display proteins, peptides, or other biologics.
   Evaluate protein stability, localization, and bioactivity post-engineering.
   
   RBC-based Therapeutic DevelopmentDesign and execute functional assays to assess therapeutic efficacy of engineered RBCs.
   Collaborate on in vivo models to evaluate biodistribution, immune responses, and pharmacodynamics
   Mentorship & Training
   • Supervise and mentor research assistants, graduate students, and undergraduate interns
   Additional Duties
   • Undertake other tasks assigned by the Principal Investigator or project leads as needed.
   

The applicant should:

• Hold a PhD in Biotechnology, Molecular Biology, Biochemistry, RNA Biology, or a related field.

Essential Qualifications & Attributes

Red Blood Cell Engineering Experience

• Hands-on experience with primary erythroid cultures, immortalized erythroid progenitor cell lines, or ex vivo RBC production systems.
• Skilled in flow cytometry, magnetic separation, and enucleation assays for erythroid lineage tracking and quality control.
• Familiarity with ethical guidelines and biosafety considerations in handling blood-derived materials and genetically modified cells.

Synthetic Biology Skills for RBC Platforms

• Proficiency in genetic construct design, vector engineering, and transgene integration for expression in erythroid cells.
• Experience with protein or nucleic acid loading strategies in mature RBCs or erythroid precursors.
• Competence in troubleshooting gene expression systems and optimizing yield, stability, and functional output of engineered RBCs.

Experimental Design & Execution

- Ability to design and conduct RNA/protein expression analyses, enzymatic assays, and studies of RNA chemical modifications.

Research Excellence

- Strong record of high‑impact, peer‑reviewed international publications.

Professional Qualities

- Independent, highly motivated, and detail‑oriented.

- Effective collaborator in multidisciplinary research environments.

Remuneration will be commensurate to the candidate's qualifications and experience. Informal enquiries are welcome and should be made to Ms Suhana Sulaiman , at

Formal application: Please submit your application, indicating job reference number and current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of 3 referees). Only shortlisted candidates will be notified.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The Synthetic Biology Translational Research Programme (TRP) at the National University of Singapore Yong Loo Lin School of Medicine is seeking talented postdoctoral or research fellows to join our team.

Synthetic Biology TRP – Research Fellow

The Synthetic Biology Translational Research Programme (TRP) focuses on engineering red blood cells for therapeutic applications, including drug delivery, immune modulation, and gene therapy. We are developing novel erythrocyte-based platforms that leverage the unique properties of RBCs for synthetic biology and biomedical innovation.

We invite applications for a highly motivated Research Fellow (RF) to work closely with the Principal Investigator and a multidisciplinary team. The position is offered on an initial one-year contract, renewable subject to performance and funding. A Ph.D. in cell biology, molecular biology, synthetic biology, or a related field is required.

1. RBC Genomics and TranscriptomicsAnalyze gene expression and genomic regulation of erythroid differentiation.
   Characterize key transcriptional and epigenetic programs governing RBC development and function.
   
2. RBC Engineering and Expression SystemsDevelop workflows for genetic modification of erythroid progenitors and immortalized RBC lines.
   Optimize lentiviral and non-viral gene delivery systems to express therapeutic payloads in RBCs.
   
3. Protein Loading and Display in RBCsEngineer red blood cells to load or surface-display proteins, peptides, or other biologics.
   Evaluate protein stability, localization, and bioactivity post-engineering.
   
4. RBC-based Therapeutic DevelopmentDesign and execute functional assays to assess therapeutic efficacy of engineered RBCs.
   Collaborate on in vivo models to evaluate biodistribution, immune responses, and pharmacodynamics.
   
5. Mentorship & Training
   • Supervise and mentor research assistants, graduate students, and undergraduate interns.
6. Additional Duties
   • Undertake other tasks assigned by the Principal Investigator or project leads as needed.

The applicant should:

• Hold a PhD in Biotechnology, Molecular Biology, Biochemistry, RNA Biology, or a related field.

Essential Qualifications & Attributes

Red Blood Cell Engineering Experience

• Hands-on experience with primary erythroid cultures, immortalized erythroid progenitor cell lines, or ex vivo RBC production systems.
• Skilled in flow cytometry, magnetic separation, and enucleation assays for erythroid lineage tracking and quality control.
• Familiarity with ethical guidelines and biosafety considerations in handling blood-derived materials and genetically modified cells.

Synthetic Biology Skills for RBC Platforms

• Proficiency in genetic construct design, vector engineering, and transgene integration for expression in erythroid cells.
• Experience with protein or nucleic acid loading strategies in mature RBCs or erythroid precursors.
• Competence in troubleshooting gene expression systems and optimizing yield, stability, and functional output of engineered RBCs.

Experimental Design & Execution

- Ability to design and conduct RNA/protein expression analyses, enzymatic assays, and studies of RNA chemical modifications.

Research Excellence

- Strong record of high‑impact, peer‑reviewed international publications.

Professional Qualities

- Independent, highly motivated, and detail‑oriented.

- Effective collaborator in multidisciplinary research environments.

Remuneration will be commensurate to the candidate's qualifications and experience. Informal enquiries are welcome and should be made to

Ms Suhana Sulaiman , at

Formal application: Please submit your application, indicating job reference number and current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of 3 referees). Only shortlisted candidates will be notified.

Research Fellow (Synthetic Biology & Enzyme Design)

Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore

The School of Biological Sciences (SBS), part of the College of Science, was established in 2002 with a mission to advance biological and biomedical sciences. At SBS, our research spans various areas, including infectious diseases, immunology, neurodegenerative diseases, telomere biology, and genome function. Over the years, SBS has attracted talented individuals from around the world and Singapore to join as scientific leaders and researchers.

We are seeking a highly motivated Research Fellow (RF) to join our team in the field of synthetic biology and enzyme design. This role focuses on developing novel biocatalysts and synthetic pathways through cutting-edge research. The successful candidate will contribute to impactful projects while gaining exposure to advanced methodologies in synthetic biology.

Key Responsibilities:

1. Lead the design, construction, and optimization of synthetic biological systems and enzyme engineering workflows.
2. Execute advanced molecular biology techniques, including DNA manipulation, PCR, and molecular cloning.
3. Conduct protein expression, purification, and characterization using methods such as spectrophotometry, HPLC, and SDS-PAGE.
4. Analyze experimental data, maintain meticulous records, and contribute to manuscript preparation for high-impact journals.

Job Requirements:

1. PhD in Biochemistry, Molecular Biology, Synthetic Biology, or a related field (completed or near completion).
2. Strong expertise in molecular cloning, protein engineering, and synthetic biology tools (e.g., CRISPR, metabolic pathway design).
3. Ability to work independently, solve complex problems, and manage multiple priorities in a fast-paced research environment.

Interested candidates should submit the following documents:

1. A cover letter detailing research interests and relevant experience.
2. A current CV, including contact information for two references.
3. Transcripts (if applicable).

The College of Science seeks a diverse and inclusive workforce and is committed to equality of opportunity. We welcome applications from all and recruit on the basis of merit, regardless of age, race, gender, religion, marital status and family responsibilities, or disability.

We regret to inform that only shortlisted candidates will be notified.

Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore

The School of Biological Sciences (SBS), part of the College of Science, was established in 2002 with a mission to advance biological and biomedical sciences. At SBS, our research spans various areas, including infectious diseases, immunology, neurodegenerative diseases, telomere biology, and genome function. Over the years, SBS has attracted talented individuals from around the world and Singapore to join as scientific leaders and researchers.

Position Available: Research Fellow

Join the laboratory of Lei Lu at the School of Biological Sciences, where we are seeking a motivated and talented Research Fellow to contribute to an exciting project focused on the endocytic trafficking of lipid nanoparticles.

Lipid nanoparticles (LNPs) have gained global attention, especially with their approval for mRNA vaccine delivery during the COVID-19 pandemic, saving millions of lives worldwide. Beyond vaccines, LNPs hold immense potential as delivery vehicles for various therapeutic nucleic acids, offering promising treatment strategies for many diseases. Despite their enormous success, the intracellular transport of LNPs — how they move within mammalian cells and deliver their nucleic acid payloads — remains poorly understood.

As part of our team, the candidate will use advanced light microscopy to explore and elucidate the molecular and cellular mechanisms governing the endocytic trafficking and intracellular delivery of LNPs. This project aims to deepen our understanding of these mechanisms, contributing to the optimization of LNP-based therapies.

Job Description

• Conduct cutting-edge research using high-resolution light microscopy to study LNP trafficking.
• Investigate endocytic pathways and payload delivery molecular mechanisms.
• Collaborate with a multidisciplinary team to advance the field of nanoparticle-based therapeutics.
• Perform any other duties as assigned.

Job Requirements

• PhD in cell biology or related fields, with a focus on membrane trafficking.
• Experience in light microscopy.
• Strong written and verbal communication skills in English - essential for data analysis and communication with stakeholders
• Strong publication record.
• Entry-level candidates are welcome to apply.

The College of Science seeks a diverse and inclusive workforce and is committed to equality of opportunity. We welcome applications from all and recruit on the basis of merit, regardless of age, race, gender, religion, marital status and family responsibilities, or disability.

Interested applicants are invited to apply directly at our NTU Career Portal .

We regret that only shortlisted candidates will be notified.

Join to apply for the Senior Research Fellow (Molecular Biology/Biochemistry & Structural Biology) role at Nanyang Technological University Singapore

Join to apply for the Senior Research Fellow (Molecular Biology/Biochemistry & Structural Biology) role at Nanyang Technological University Singapore

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NTU Institute of Structure Biology (NISB) provides a complete pipeline for Structural Biology to accelerate discovery in basic and applied Bioscience.

At NISB, we aim to integrate a comprehensive set of Structural Biology tools to address fundamental questions in biology, to understand human diseases and to accelerate structure-based drug discovery. We have the expertise and equipment to bring your gene of interest from plasmid to atomic level structure using a series of state-of-the art platforms for Protein expression, biophysical characterization and imaging using cryo-EM, tomography or X-ray crystallography.

For more details, please view Responsibilities

We are looking for a Senior Research Fellow to play a leading role in running NISB in close partnership with the NISB Director. This role offers a unique opportunity to drive impactful research while fostering collaboration and innovation in a dynamic scientific environment. The job scope includes:

• Collaborate with various academic and industry users of NISB facilities to define their needs and to help design and perform the experiments together with the core NISB team;
• Lead the NISB core team to ensure timely delivery of quality samples and deliverables (overexpressed protein, structure with proper protocol and documentation;
• Work with the core team to maintain accurate and comprehensive reporting and documentation for tasks commissioned by academic and industry users;
• Support NISB Director in advocating for NISB’s activities and technological platforms to enhance visitibility and engagement with stakeholders;
• Contribute to in-house research and platform technological development : the successful candidate can pursue independent research in structural biology or biotechnology aligned with the institute’s interest in protein structure and engineering.
  
  

• A PhD degree in Molecular Biology, Biochemistry, Structural Biology, Biotechnology or related field
• At least 2 years of relevant experiences in similar role / technical hands-on experience in protein related work
• Possesses international experience, acquired through postdoctoral experience documented by relevant publications
• Good written and oral communication skills
• Proficiency in handling software to collect and process Structural Biology data (XDS, CCP4, Phenix for X-ray crystallography and Cryosparc, Relion for Cryo-EM
• Very good publication record in international peer reviewed journals in relevant fields
• Strong ability to work independently, to develop solutions under strict timelines, meticulous and eye for details Excellent organizational and time management skills
• Demonstrates strong collaboration skills by working effectively with diverse academic and industry stakeholders, as well as thriving in a fast-paced environment alongside the NISB core team
  
  

• Seniority level Mid-Senior level

• Employment type Full-time

• Job function Research, Analyst, and Information Technology
• Industries Higher Education

Referrals increase your chances of interviewing at Nanyang Technological University Singapore by 2x

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Pioneer, West Region, Singapore 2 weeks ago

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Profs Greg-Tucker-Kellogg (Biological Sciences) on bioinformatics research to understand the detailed role of non-canonical splicing dysregulation in models of human disease

The main responsibilities of the position include:

• Bioinformatics analysis (in Python, R, and using workflow tools such as Snakemake and Nextflow
• Development and modification of algorithms used for analysis of transcriptome dysregulatio
• Report writing

Bachelor or Masters degree in bioinformatics, biotechnology or equivalen

Skills:

• Demonstrated strong coding skills in Python and R are a must
• Domain-specific experience in analysis of transcriptome dysregulation and disease-associated alternative splicing
• Strong workflow development skills in Snakemake or Nextflow
• Excellent communication in written and spoken English
• Demonstrated success in collaborative, interdisciplinary research.

Experience:

• At least 1 year of practical research experience in a closely related area

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Prof Greg Tucker-Kellogg on experimental cancer biology models for epigenetic drug discovery.

The main responsibilities of the position include:

• Mammalian cell culture research and imaging of epigenetic marks at individual loc
• Epigenetic drug inhibition studies followed by molecular and cellular assays

Bachelor or Masters degree in biotechnology or a closely related discipline

Skills:

• Mammalian cell culture of both suspension and adherent cells
• Confocal microscop
• Fluorescent in situ hybridisatio
• Design of DNA nanostructures for novel assays

Experience:

• At least 1 year of experience in experimental cancer biology research with a demonstrated track record of troubleshooting novel assay design