34 Pharmaceutical Scientist jobs in Singapore

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Dr TIAN Chong on synthesis of mechanically interlocked molecules under a project on Bridging Chemistry and Biology: Synthesis, Structure and Properties of Mechanically Interlocked Peptides (MIPS).

The main responsibilities of the position include:
• Research tasks (90%): to carry out research to design and synthesize rotaxanes via novel active template strategies.
• Laboratory safety/ordering (10%): to aid in ordering and maintaining lab supplies, create and review standard operating procedures and risk assessments, assemble reagents, chemicals and media that are needed for experiments.

• PhD of Science required with major in Organic Chemistry. Candidate with strong background in organic synthesis and excellent record of publication is preferred.

Skills:
1. Have an excellent understanding of chemistry.
2. Have expertise in multi-step synthesis.
3. Communicate well in English in writing and in oral and visual presentations.
4. Show an ability to work supportively in a laboratory environment.

Experience:

• Experience in organic synthesis and spectroscopic techniques for compound characterization.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Dr TIAN Chong on synthesis of mechanically interlocked molecules under a project on Bridging Chemistry and Biology: Synthesis, Structure and Properties of Mechanically Interlocked Peptides (MIPS).

The main responsibilities of the position include:
• Research tasks (90%): to carry out research to design and synthesize rotaxanes via novel active template strategies.
• Laboratory safety/ordering (10%): to aid in ordering and maintaining lab supplies, create and review standard operating procedures and risk assessments, assemble reagents, chemicals and media that are needed for experiments.

• PhD of Science required with major in Organic Chemistry. Candidate with strong background in organic synthesis and excellent record of publication is preferred.

Skills:
1. Have an excellent understanding of chemistry.
2. Have expertise in multi-step synthesis.
3. Communicate well in English in writing and in oral and visual presentations.
4. Show an ability to work supportively in a laboratory environment.

Experience:

• Experience in organic synthesis and spectroscopic techniques for compound characterization.

The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.

Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.

Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.

Esco Aster.

One World Biosolutions for One Health.

Who we’re looking for

Physical/Mental Requirements/Work Environment

· Ability to read, analyze and interpret scientific data and publications.

· Ability to author or review protocols, technical reports and technology transfer documents.

· Ability to author and review standard operating procedures, batch records, protocols, data, reports and other related documents.

· Ability to define problems, collect data, establish facts, and draw conclusions.

· Repetitive motions due to certain laboratory techniques.

· Ability to adapt and keep up with rapid changes in a fluid and dynamic environment as this is a rapidly evolving space.

The Scope

You will be part of Esco Aster’s scientific division and contribute to the company’s CDMO mission and objectives. You will perform research and process development activities, in various projects and in collaboration with internal and external stakeholders, clients and partners.

Primary Work Location: Ayer Rajah Crescent, Singapore

Job Responsibilities

Design and Independently Execute Experiments:

· Design and laboratory-scale experiments to support client upstream processes and requests.

· Perform assay development and data analysis.

Upstream Process Evaluation and Optimization:

· Evaluate and optimize existing client processes in preparation for scale-up.

· Propose improvements and modifications to enhance process efficiency.

Scale-Up and Technology Transfer:

· Conduct scale-up experiments in larger bioreactors.

· Adapt processes to align with available on-site equipment.

· Facilitate technology transfer from clients, aiming at scaling up processes or implementing new technologies (e.g., perfusion, serum replacements).

Continuous Process Improvement:

· Proactively identify opportunities for process improvements.

· Initiate and drive enhancements to streamline processes.

Project Management and Documentation:

· Write client proposals, outlining milestones, timelines, and budgets for scale-up projects.

· Take ownership and accountability for all deliverables and milestones in assigned projects.

· Summarize project work in a formal report and communicate effectively to stakeholders.

Cross-Functional Collaboration:

· Collaborate across different teams to troubleshoot, test, and optimize various issues.

· Work seamlessly in a cross-functional environment.

Subject Matter Expert Support:

· Support sales, business development, product specialists, and associated departments as a subject matter expert.

Ad Hoc Tasks:

· Undertake other tasks as assigned based on project needs.

Flexible Work Schedules:

Adapt work schedules as needed to accommodate cell culture schedules.

Requirements

· Minimum Master’s degree in Biology or related science.

· At least 1-2 years related laboratory experience in mammalian cell culture, stem cells, immunology or exosomes.

· Experience with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP) will be an advantage.

· Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).

· Experience in isolation of stem cells, tissue banking and generation of cell bank.

· Experience with cell assays such as FACS, ELISA, biological assays.

· Experience with bioreactor systems.

· General laboratory skills, good pipetting skills and experience with automation.

· Strong computer, scientific, and organizational skills.

· Excellent communication (oral and written) and attention to detail.

· Strong team player, develop positive relationship with a strong set of interpersonal skills.

· Ability to work independently and as part of a team, self-motivated, adaptable, and has a positive attitude.

· Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.

· Good presentation skills.

· A friendly and pleasant disposition.

Interested candidates, please submit a Cover Letter and CV to

Duties & Responsibilities

• Design and conduct experiments to address research objectives.
• Develop and optimize protein purification protocols to ensure high purity, yield, and activity.
• Execute and troubleshoot purification processes, including chromatography (affinity, ion exchange, size exclusion), filtration, and ultracentrifugation.
• Stay updated on scientific advancements through literature reviews.
• Perform laboratory work, including sample preparation, data collection, and analysis.
• Interpret results, draw conclusions, and present findings through reports and presentations.
• Collaborate with scientists, engineers, and cross-functional teams on research and product development.
• Maintain accurate experimental records in compliance with company policies and regulations.
• Assist in preparing research proposals, grant applications, and publications.
• Participate in scientific conferences, seminars, and workshops.

Requirements

Education:

• Bachelor's degree or higher in Biology, Chemistry, Biochemistry, Molecular Biology, or related fields.

Experience:

• 3-8 years of research experience in academia or industry, with a strong track record of scientific innovation.
• Experience in upscaling to production is a plus.

Technical Expertise:

• Proficiency in protein purification, cell culture, and relevant laboratory techniques.
• Strong knowledge of experimental design, data analysis, and statistical tools.
• Hands-on experience with purification techniques, including chromatography (affinity, ion exchange, size exclusion), filtration, and ultracentrifugation.

Skills & Competencies:

• Strong problem-solving skills, attention to detail, and ability to work independently and collaboratively.
• Excellent communication, presentation, and interpersonal skills.
• Familiarity with regulatory requirements and quality standards in scientific research.

Job no: 498802
Department: Food, Chemical and Biotechnology
Contract type: Contract
Apply now

As a University of Applied Learning, SIT works closely with industry in our research pursuits. Our research staff will have the opportunity to be equipped with applied research skill sets that are relevant to industry demands while working on research projects in SIT.

The primary responsibility of this role is to deliver on a Pharmaceutical Innovation Programme Singapore research project where you will be part of a collaborative team exploring innovative ways of understanding extrusion processing for pharmaceutical drug materials and products using rheological measurements.

Key Responsibilities

In this role, you will characterize mixtures of pharmaceutical excipients and drug materials to develop methodologies for screening hot-melt extrusion formulations and selecting optimal operating conditions using rheology, with the objective of producing amorphous-solid-dispersions. You will validate the developed processing space and operating conditions for extruded pharmaceutical formulations using a lab-scale extruder. In collaboration with researchers at the Singapore-MIT Alliance for Research and Technology (SMART), you will characterize the physical properties and performance of intermediate pharmaceutical drug products. The created methods will be transferred to the industrial partner to enhance their product development process using rheological characterization.

More specific responsibilities include:

• Participate in and manage the research project with Principal Investigator (PI), and the research team members to ensure all project deliverables are met.
• Undertake characterization of pharmaceutical active ingredients, polymeric excipients, and plasticizers for producing amorphous-solid-dispersions.
• Perform lab-scale hot-melt extrusion of pharmaceutical materials to validate predicted processing conditions and product outcomes.
• Collaborate with broader pharmaceutical research team at SMART.
• Design, execute, and interpret experiments independently.
• Author papers in high-quality journals in areas that are related to the research.
• Prepare and deliver reports and presentations for industrial partners
• Carry out Risk Assessment, and ensure compliance with Work, Safety and Health Regulations.
• Coordinate procurement and liaise with vendors/suppliers.
• Work independently, as well as within a team.

Job Requirements

• Have deep hands-on experience with at least one of the areas of polymer rheology, extrusion processing, pharmaceutical engineering with small molecules.
• Relevant competence in the areas of wet lab work, analytical instrumentation, material science and formulation
• Have an advanced degree in chemical engineering, mechanical engineering, materials science and engineering, or a related field.
• Knowledge of any of the following will be advantageous: rheology, physical characterisation, crystallisation, polymer melts, extrusion, material physics.
• Able to build and maintain strong working relationships with people within and external to the university.
• Self-directed learner who believes in continuous learning and development.
• Proficient in communicating via technical writing and presentations.
• Possess strong analytical and critical thinking skills.
• Show strong initiative and take ownership of work.

Apply now
Advertised: 11 Nov 2024 Singapore Standard Time
Applications close: 30 Jun 2025 Singapore Standard Time

Organisation/Company SINGAPORE INSTITUTE OF TECHNOLOGY (SIT) Research Field Engineering Chemistry Engineering Researcher Profile First Stage Researcher (R1) Country Singapore Application Deadline 31 Dec 2025 - 00:00 (UTC) Type of Contract Other Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

As a University of Applied Learning, SIT works closely with industry in our research pursuits. Our research staff will have the opportunity to be equipped with applied research skill sets that are relevant to industry demands while working on research projects in SIT.

The primary responsibility of this role is to deliver on a Pharmaceutical Innovation Programme Singapore research project where you will be part of a collaborative team exploring innovative ways of understanding extrusion processing for pharmaceutical drug materials and products using rheological measurements.

Key Responsibilities

In this role, you will characterize mixtures of pharmaceutical excipients and drug materials to develop methodologies for screening hot-melt extrusion formulations and selecting optimal operating conditions using rheology, with the objective of producing amorphous-solid-dispersions. You will validate the developed processing space and operating conditions for extruded pharmaceutical formulations using a lab-scale extruder. In collaboration with researchers at the Singapore-MIT Alliance for Research and Technology (SMART), you will characterize the physical properties and performance of intermediate pharmaceutical drug products. The created methods will be transferred to the industrial partner to enhance their product development process using rheological characterization.

More specific responsibilities include:

• Participate in and manage the research project with Principal Investigator (PI), and the research team members to ensure all project deliverables are met.
• Undertake characterization of pharmaceutical active ingredients, polymeric excipients, and plasticizers for producing amorphous-solid-dispersions.
• Perform lab-scale hot-melt extrusion of pharmaceutical materials to validate predicted processing conditions and product outcomes.
• Collaborate with broader pharmaceutical research team at SMART.
• Design, execute, and interpret experiments independently.
• Author papers in high-quality journals in areas that are related to the research.
• Prepare and deliver reports and presentations for industrial partners
• Carry out Risk Assessment, and ensure compliance with Work, Safety and Health Regulations.
• Coordinate procurement and liaise with vendors/suppliers.
• Work independently, as well as within a team.

Job Requirements

• Have deep hands-on experience with at least one of the areas of polymer rheology, extrusion processing, pharmaceutical engineering with small molecules.
• Relevant competence in the areas of wet lab work, analytical instrumentation, material science and formulation
• Have an advanced degree in chemical engineering, mechanical engineering, materials science and engineering, or a related field.
• Knowledge of any of the following will be advantageous: rheology, physical characterisation, crystallisation, polymer melts, extrusion, material physics.
• Able to build and maintain strong working relationships with people within and external to the university.
• Self-directed learner who believes in continuous learning and development.
• Proficient in communicating via technical writing and presentations.
• Possess strong analytical and critical thinking skills.
• Show strong initiative and take ownership of work.

Job no: 498802
Department: Food, Chemical and Biotechnology
Contract type: Contract
Apply now

As a University of Applied Learning, SIT works closely with industry in our research pursuits. Our research staff will have the opportunity to be equipped with applied research skill sets that are relevant to industry demands while working on research projects in SIT.

The primary responsibility of this role is to deliver on a Pharmaceutical Innovation Programme Singapore research project where you will be part of a collaborative team exploring innovative ways of understanding extrusion processing for pharmaceutical drug materials and products using rheological measurements.

Key Responsibilities

In this role, you will characterize mixtures of pharmaceutical excipients and drug materials to develop methodologies for screening hot-melt extrusion formulations and selecting optimal operating conditions using rheology, with the objective of producing amorphous-solid-dispersions. You will validate the developed processing space and operating conditions for extruded pharmaceutical formulations using a lab-scale extruder. In collaboration with researchers at the Singapore-MIT Alliance for Research and Technology (SMART), you will characterize the physical properties and performance of intermediate pharmaceutical drug products. The created methods will be transferred to the industrial partner to enhance their product development process using rheological characterization.

More specific responsibilities include:

• Participate in and manage the research project with Principal Investigator (PI), and the research team members to ensure all project deliverables are met.
• Undertake characterization of pharmaceutical active ingredients, polymeric excipients, and plasticizers for producing amorphous-solid-dispersions.
• Perform lab-scale hot-melt extrusion of pharmaceutical materials to validate predicted processing conditions and product outcomes.
• Collaborate with broader pharmaceutical research team at SMART.
• Design, execute, and interpret experiments independently.
• Author papers in high-quality journals in areas that are related to the research.
• Prepare and deliver reports and presentations for industrial partners
• Carry out Risk Assessment, and ensure compliance with Work, Safety and Health Regulations.
• Coordinate procurement and liaise with vendors/suppliers.
• Work independently, as well as within a team.

Job Requirements

• Have deep hands-on experience with at least one of the areas of polymer rheology, extrusion processing, pharmaceutical engineering with small molecules.
• Relevant competence in the areas of wet lab work, analytical instrumentation, material science and formulation
• Have an advanced degree in chemical engineering, mechanical engineering, materials science and engineering, or a related field.
• Knowledge of any of the following will be advantageous: rheology, physical characterisation, crystallisation, polymer melts, extrusion, material physics.
• Able to build and maintain strong working relationships with people within and external to the university.
• Self-directed learner who believes in continuous learning and development.
• Proficient in communicating via technical writing and presentations.
• Possess strong analytical and critical thinking skills.
• Show strong initiative and take ownership of work.

Apply now
Advertised: 09 Dec 2024 Singapore Standard Time
Applications close: 30 Jun 2025 Singapore Standard Time

Research Scientist, Pharmacology - Hummingbird Bioscience

Full time position – Singapore-based location

ABOUT HUMMINGBIRD BIOSCIENCE

Hummingbird Bioscience is a biotherapeutics company working at the interface of artificial intelligence and human innovation to discover and develop transformative medicines for hard-to-treat diseases. Hummingbird Bioscience’s computational and systems biology technologies have generated a pipeline of innovative clinical-stage monoclonal antibodies and antibody-drug conjugates in oncology and autoimmunity. At Hummingbird Bioscience, the commitment to rigorous science, teamwork, and intellectual integrity underpins our passion to accelerate the journey of new drugs from concept to clinic.

For more information, please visit , and follow Hummingbird Bioscience on LinkedIn , X (formerly Twitter) , and YouTube .

About the role

Hummingbird Bioscience is seeking a Research Scientist – Preclinical pharmacology to support the Pharmacology team. This will be a permanent role for the right candidate with ample opportunity to learn, grow and contribute to innovative drug development projects. The ideal candidate is a highly organized and proactive individual with a background in life sciences and a collaborative mindset who thrives in a fast-paced biotech environment.

Key responsibilities

• Coordinate the execution of in vitro and in vivo preclinical studies by interfacing with internal scientific teams and external CROs; ensure alignment on study design, timelines, logistics, and data collection to support key development milestones
• Support study start-up and execution by reviewing and organizing study plans, protocols, contracts and communication workflows
• Manage procurement, shipment, and inventory processes for reagents, samples, and study-related materials
• Perform literature review, data analysis and support preparation of reports, presentations, and dashboards to aid project tracking and decision-making

Essential qualifications

• PhD in a scientific discipline such as biology, biomedical sciences or a related field
• At least 1–2 years of hands-on experience managing preclinical research projects, preferably in cancer biology and immunology, within biotech, pharma, or academic settings
• Proficiency in MS office and data analysis tools such as GraphPad
• Prior experience of working in a CRO environment
• Strong communication and interpersonal skills, with proficiency in English and Mandarin to facilitate effective collaboration with external stakeholders and CROs, including those based in China

Desirable qualifications

• Background or experience working with therapeutic antibodies and or antibody-drug conjugates

OUR MISSION & VALUES

Our fast-growing biotechnology company is committed to discovering and developing important new drugs for cancer and autoimmune diseases, and living by our values: Excellence, Determination, Teamwork, Intellectual Integrity and Audacity.

JOIN US AT THE FRONTIER OF DRUG DISCOVERY AND DEVELOPMENT

We are looking for passionate and motivated individuals committed to solving important, complex problems. We are committed to the personal and professional development of our team and offer robust learning and development programs. Hummingbird Bioscience understands the need for flexibility for our team and offers a generous paid time off program with flexibility to support employees through different life stages. We invest in our team’s health by offering competitive benefits including health and dental insurance, and a comprehensive and holistic employee assistance program. We foster a more collaborative, productive, and sociable culture with on-site lunches and snacks. Finally, we believe in creating social impact beyond our business through corporate social responsibility initiatives.

Are you ready to join us on our mission to discover and develop important new drugs for cancer and autoimmune disease? Click on ‘Apply for this Job’ to submit your application.

For further enquiries, please email us at .

Hummingbird Bioscience is firmly committed to Equal Employment Opportunity (EEO) and to compliance with all Singapore and US federal, state and local laws and/or guidelines that prohibit employment discrimination on the basis of age, race, color, gender, sexual orientation, gender identity, ethnicity, national origin, citizenship, religion, genetic carrier status, disability, pregnancy, childbirth or related medical conditions, marital status, protected veteran status and other protected classifications.

Job Overview

We're seeking talented AI Research Scientists to drive innovation in AI research and development. You'll conduct cutting-edge research, develop AI-enabled products, and collaborate with world-class organisations.

Key Responsibilities

- Conduct research in recommendation & search, natural language processing, computer vision, and large language models

- Develop AI-enabled products and services with cross-functional teams

- Collaborate with academia and industry partners on projects

Requirements

- PhD degree in Computer Science, Statistics, Applied Mathematics, or equivalent research experience

- 3+ years of experience in AI research and development, with expertise in areas of Recommendation & search, AIGC, High-performance Computing, Vision Large Language Models, Machine learning or similar areas

- Strong programming skills in languages such as C/C++, Java, or Python

- Ability to generate new ideas and innovate

Ideal Candidate

- Passionate about advancing AI research and development

- Strong track record of research and innovation

- Excellent collaboration and communication skills