136 Pharmaceutical Scientist jobs in Singapore

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Dr. LIU Shi on the design of GPCR-targeting peptidic ligands and related functional evaluation.

The main responsibilities of the position include:
1. To synthesize small-molecule building blocks for SPPS
2. To synthesize GPCR-targeting peptidic ligands
3. Functional evaluation of designed peptides in cell assays

• Qualifications / Discipline: PhD degree in organic chemistry or medicinal chemistry
• Skills: Organic synthesis and medicinal chemistry
• Experience: Experienced in synthetic organic chemistry and drug design

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Dr Gloryn Chia on the development of immunotherapy strategies under a project on Advancing Immunotherapy Platforms to Overcome Tumor Resistance.

The main responsibilities of the position include:
• Assisting with laboratory research focused on immunotherapy and mechanisms of tumor resistance.
• Performing routine experiments and supporting the setup of new assays.
• Managing sample processing, data collection, and basic data analysis.
• Maintaining accurate experimental records and assisting with documentation for reports and publications.
• Supporting day-to-day lab operations, including inventory and equipment maintenance.
• Working collaboratively with other team members and contributing to a positive research environment.

Qualifications / Discipline: Bachelor’s degree in Biomedical Research or a related life science discipline.

Skills: Bioinformatics.

Experience: Prior experience with bioinformatics tools (e.g., RNA-seq analysis, gene expression profiling) will be advantageous.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Associate Professor Doreen Tan on Academic Development of Personalised Medicine under a project on DTSY Statin.

The main responsibilities of the position include:
1. Oversee project timelines, milestones and governance of ethics and recruitment processes.
2. Keep a track of budgeting and the management of resources, especially in manpower and consumables.
3. Assist in literature search and drafting and review of grants.
4. Organise related training workshops.

Qualifications / Discipline:
- PhD in related discipline.
- Candidates in the final stages of PhD studies are welcome to apply.

Skills:
- Project Management.
- Statistics skills.

Experience:
- Experience in project management and data handling.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notifie

The successful candidate will work with Dr. Liu Shi on studying signaling modes and underlying molecular mechanisms of certain GPCRs that are relevant to metabolic diseases.

The main responsibilities of the position include:
- Developing various cell assays to investigate GPCR signaling.
- Performing molecular biology experiments to study the GPCR interactome.
- Assisting with the maintenance of lab biosafety.

Qualifications / Discipline:
- Candidates should hold a Bachelor's or Master's degree in Biological Science or a related field.
- Proficiency in molecular and cell biology experiments is required.

Skills:
- Candidates should have experience with a range of techniques, including mammalian cell culture, stable cell line construction, western blot, quantitative PCR, and confocal microscopy.
- Experience with chemoproteomics would be considered a strong advantage.

Experience:
- Candidates are expected to have a minimum of 1-2 years of hands-on experience in a biology lab and the ability to independently conduct routine molecular and cell biology experiments.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The laboratory of Professor Giorgia Pastorin at the National University of Singapore (NUS) is currently recruiting a (Postdoctoral) Research Fellow.

We are seeking for a motivated and competent post-doctoral fellow to work on funded research project aimed at deciphering the roles of MOAP-1 in cellular senescence and ageing-associated disorders in liver. Long term goal of the project is to gain novel insights towards developing viable approaches for mitigating development and progression of liver NAFLD-associated liver diseases including MASH and HCC, as well as developing novel nanoformulations that enhance the accumulation of actives at the disease site.

Successful candidate will have the opportunity to work with a multidisciplinary team as well as collaborators in Singapore and overseas.

To facilitate a better understanding of the work being pursued in the laboratory, prospective applicants can refer to the following papers:

1. K.O. Tan et al., MAP-1 is a mitochondrial effector of Bax, (Track II), Proc. Natl. Acad. Sci. USA, 102: 14623-14688, 2005.
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2. N.Y. Fu et al., Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria, (Track II), Proc. Natl. Acad. Sci. USA, 104: 10051-10056, 2007.

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3. N.Y. Fu et al., Baxbeta: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism, Molecular Cell, 33: 15-29, 2009.

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4. S.K. Sukumaran et al., A soluble form of the pilus protein FimA targets the VDAC-hexokinase complex at mitochondria to inhibit host cell apoptosis, Molecular Cell, 37: 768-783, 2010.

(
5. C.T. Tan et al., MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria, Cell Reports, 16:174-85, 2016.
(
6. C.T. Tan et al., MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling, EMBO Reports, 22: e50854, 2021. (Featured as the cover story in Jan, 2021 issue:
7. H.C. Chang et al., The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore, Autophagy, 2021. (
8. C.T. Tan et al., p62/SQSTM1 in liver diseases: the usual suspect with multifarious identities. FEBS J, 290: 892-912, 2023. (

Responsibilities include:
• Planning and execution of experiments.
• Collect and analyze research data.
• Guiding and working with junior staffs, including graduate/undergraduate students.
• Participation in preparation of manuscripts and other reports.
• Uphold research integrity and ensure safety compliance.
• Perform other related duties incidental to the work described therein.

Interested candidates please submit a detailed curriculum vitae, contact information of 3 referees and indicate your earliest availability.

Please note that only shortlisted candidates will be notified.

Qualifications / Discipline:
• Ph.D. degree in Molecular Biology, Biochemistry, Cancer Biology or other related fields is preferred.

Skills:
• Good communication skills and a team player.
• Effective oral and written management communication skills.
• Ability to work in a fast-paced environment.
• Other desirable attributes: self-motivated, organized, meticulous, efficient, and flexible.

Experience:
• Applicants with research experiences of at least 4 years in mouse models and/or molecular and cell biology techniques (e.g., primary cell preparations, CRISPR-Cas9 gene editing, confocal microscopy, FACS, histology, IHC, IF or protein-protein interaction) are preferred.

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

The successful candidate will work with Dr Brandon I Morinaka on Production and characterization of new natural products under a project on Genome Mining For Peptide Natural Products And Biosynthetic Enzymes.

The main responsibilities of the position include:
• Production of new peptide natural products in E. coli.
• Characterization of new natural products using spectroscopic techniques.
• Biological evaluation of new natural products for antimicrobial activity.

• Qualifications / Discipline: BSc in pharmacy, chemistry, biology or field related to research.
• Skills: Biochemistry, molecular biology, analytical chemistry
• Experience: Previous research experience in natural products chemistry and biosynthesis.

• Provide scientific leadership and direction for a multidisciplinary research team focused on biomass valorization and continuous-flow process development.
• Act as the scientific and operational anchor between MPI (Germany) and NTU (Singapore), facilitating effective cross-national coordination.
• Lead the design, commissioning, and operation of the Automated Flow Chemistry Laboratory, including layout design, staffing, and procurement.
• Drive the development and optimization of closed-loop, automated flow chemistry systems for biomass valorization, integrating data-driven design and in-line analytics.
• Ensure effective project management, team coordination, and progress reporting, while maintaining high standards of safety and scientific rigor.
• Mentor and guide a team of 5-6 researchers, including Research Fellows and Assistants.
• Oversee project progress, ensure milestone achievements, and contribute to the drafting of research proposals and industrial engagement activities.
• Disseminate results through high-impact journals, patents, and global conferences.
• Represent MPI in administrative, academic, and strategic discussions, including engagement with CREATE leadership and NRF stakeholders.

• Doctoral degree in Chemical Science, Chemical Engineering, Chemistry, or a related field.
• Strong expertise in flow chemistry, automation, Chemputer-based platforms, and closed-loop experimentation.
• Experience in digitalization of chemical synthesis, lab automation, and pilot-scale system development.Strong research portfolio with high-impact publications
• Demonstrated leadership in interdisciplinary or international research projects.
• Experience in managing lab-scale to pilot-scale chemical processes, including automation, scale-up, and data-driven optimization.
• Prior involvement in programme proposal writing, lab layout design, and research coordination is a strong plus.
• Excellent organizational, communication, and interpersonal skills with the ability to lead diverse teams and manage cross-institutional collaborations.

The role of the chemist assistant involves conducting various laboratory tests using advanced instruments such as UV-VIS, IC-POES, FIA, GC-MS etc.

The goal is to deliver prompt testing results to customers.

• Perform chemical analyses using sophisticated equipment
• Carry out sample examination and deliver results in a timely manner
• Maintain laboratory equipment in a clean and functional state
• Conduct calibration and prepare reagents when necessary
• Prepare annual assessments and collaborate with external audit teams
• Ensure a well-organized and safe laboratory environment
• Assume new responsibilities as needed, such as training interns during their internship in the lab